Development of an experimental setup for micro flow measurement using the front tracking method

Batista, Elsa; Sousa, João A.; Álvares, Miguel; Afonso, Joana; Martins, Rui F.

doi:10.1016/j.measen.2021.100152

Cited by 4 publications

(2 citation statements)

References 2 publications

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“…The flow was generated with a programmable syringe pump Nexus 3000, from Chemyx, using a 1 mL ILS glass syringe connected to a polyethylene (PE) tube of 1.26 mm (0.05") inner diameter. The front tracking method for flow measurements described in [18,19] is an optica method that consists of tracking the position of the meniscus of a liquid (liquid/air or liq uid/liquid interface) inside a (typically) capillary tube over time. An optical image acqui sition system and image processing software are used to achieve the position over time o the meniscus.…”

Section: Flow Measurementmentioning

confidence: 99%

“…Also, both polydimethylsiloxane (PDMS) and polymer chips-Cyclic Olefin Copolymer (COC), tradename TOPAS©-are used as measuring substrates to identify the influence of material on the repeatability of the results. The flow rates of the systems and associated measurement errors were studied at the IPQ Volume and Flow Laboratory using the gravimetric method [16,17] and the front tracking method [18,19]. Its main focus was to measure the connection port sizes in the microfluidic devices and components, and, accordingly, the possible existence of fluid leaks in these systems.…”

Section: Introductionmentioning

confidence: 99%

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The Importance of Dimensional Traceability in Microfluidic Systems

Batista,

Alves e Sousa,

Saraiva

et al. 2024

Metrology

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Dimensional measurements are fundamental in microfluidic device manufacturing and performance. The main focus of this study is the measurement of the connection port sizes in microfluidic devices and components and, accordingly, the possible existence of fluid leaks determined using the flow rate error. The sizes associated with three different microfluidic systems were determined using laser interferometry and through an optical measuring instrument, with metrological traceability to national length standards. It was possible to infer the method with the greatest accuracy and lowest measurement uncertainty for characterizing this kind of system. In conclusion, the results of this work directly address the current lack of dimensions measuring methods of microfluidic components by providing a comprehensive comparison of different protocols, ultimately suggesting a preferred option for immediate application within the microfluidic industry.

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Section: Flow Measurementmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Importance of Dimensional Traceability in Microfluidic Systems

Batista,

Alves e Sousa,

Saraiva

et al. 2024

Metrology

Self Cite

View full text Add to dashboard Cite

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Range Extension down to 1 mL/h of Micro Liquid Flow Calibration Facility at CSIR-NPL, India

Sanjeet Kumar,

Jaiswal,

Varshney

et al. 2024

MAPAN

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Precision and reliability study of hospital infusion pumps: a systematic review

et al. 2023

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Background Infusion Pumps (IP) are medical devices that were developed in the 1960s and generate fluid flow at pressures higher than that of normal blood pressure. Various hospital sectors make use of them, and they have become indispensable in therapies requiring continuity and precision in the administration of medication and/or food. As they are classified Class III (high risk) equipment, their maintenance is crucial for proper performance of the device, as well as patient and operator safety. The principal consideration of the pump is the volume infused, and the device demands great attention to detail when being calibrated. A lack of necessary care with this equipment can lead to uncertainty in volume and precision during the administration of substances. Because of this, it is essential to evaluate its reliability, to prevent possible failures at time of execution. This control aims at the quality of the intended infusion result, becoming an indication of quality. Methods This systematic review summarizes studies done over the last 10 years (2011 to December 2021) that address the reliability and accuracy of hospital infusion pumps, in order to identify planning of maintenance and/or other techniques used in management of the equipment. The Prisma method was applied and the databases utilized were Embase, MEDLINE/Pubmed, Web of Science, Scopus, IEEE Xplore, and Science Direct. In addition, similar reviews were studied in Prospero and the Cochrane Library. For data analysis, softwares such as Mendeley, Excel, RStudio, and VOSviewer were used, and Robvis helped in plotting risk of bias results for studies performed with Cochrane tools. Results The six databases selected produced 824 studies. After applying eligibility criteria (inclusion and exclusion), removing duplicates, and applying filters 1 and 2, 15 studies were included in the present review. It was found that the most relevant sources came from the Institute of Electrical and Electronics Engineers (IEEE) and that the most relevant keywords revolved around the terms (“device failure”, “infusion pumps”, “adverse effects”, “complications”, etc.). These results made clear that there remains substantial room for improvement as it relates to the study of accuracy and reliability of infusion. Conclusions We verified that the reliability and precision analysis of hospital infusion pumps need to be performed in a more detailed and consistent way. New developments, considering the model and IP specification, are intended, clearly explaining the adopted methodology.

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Development of an experimental setup for micro flow measurement using the front tracking method

Cited by 4 publications

References 2 publications

The Importance of Dimensional Traceability in Microfluidic Systems

The Importance of Dimensional Traceability in Microfluidic Systems

Range Extension down to 1 mL/h of Micro Liquid Flow Calibration Facility at CSIR-NPL, India

Precision and reliability study of hospital infusion pumps: a systematic review

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