Development of an Expandable Intra-aortic Prosthesis for Experimental Aortic Dissection

Long-term results of the open stent-grafting technique for extended aortic arch disease

“…Meanwhile, as an emerging, less invasive alternative to conventional surgical repair, thoracic endovascular aortic repair (TEVAR) was brought into clinical use by Dake and his colleagues 5 and reported in 1994. Our group has also been using TEVAR since 1993 after animal experimentation, 6,7 and satisfactory early outcomes were achieved for type B aortic dissection. 8 This method yielded a less invasive alternative for high-risk patients.…”

A mechanical device for aortic compliance modulation: In vitro simulation of aortic dissection treatment

“…This working hypothesis prompted us to explore an alternative acute intervention strategy. Existing experimental therapeutic approaches aim to slow or stop the dissection process by closing the aortic tears placement of intravascular stents or ''containment'' nets (Nazari et al, 1996;Eggebrecht et al, 2002;Kato et al, 1993;Inoue et al, 1999).…”

“…Active counterpulsation to provide mechanical ventricular support is generally used only in cases of extreme ventricular insufficiency, due to the risk of vascular wall damage associated with rapid balloon inflation. Development of alternative or synergistic therapeutic approaches is highly relevant (John, 2002;Fujita et al, 2003;Nazari et al, 1996;Mitchel et al, 1994;Eggebrecht et al, 2002;Kato et al, 1993). With the aim of developing a novel presurgical treatment option, we considered the possibility of introducing a passive counterpulsating damper into the dissected aorta in order to limit the physical stress associated with ventricular ejection and increase the aorto-ventricular pressure gradient in the diastolic phase.…”

The Fate of Conventional Elephant Trunk in the Frozen Elephant Trunk Era

“…[3][4][5] The use of the FET technique was initially experimental, before it was formally introduced in 1996, offering a more contemporary hybrid method, typically performed in a single stage via combining open and endovascular repair. 6,7 However, many aortic cases still require more than one intervention, as each case differs according to center experience and the demographic, anatomical, and disease characteristics of the patients. 3,8 It is useful that polyester-based FET grafts are generally clampable with good recoil and are therefore amendable to repeat intervention.…”