Development of an epigenetic clock to predict visual age progression of human skin
Agata Bienkowska,
Günter Raddatz,
Jörn Söhle
et al.
Abstract:Aging is a complex process characterized by the gradual decline of physiological functions, leading to increased vulnerability to age-related diseases and reduced quality of life. Alterations in DNA methylation (DNAm) patterns have emerged as a fundamental characteristic of aged human skin, closely linked to the development of the well-known skin aging phenotype. These changes have been correlated with dysregulated gene expression and impaired tissue functionality. In particular, the skin, with its visible man… Show more
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