Development of an enzyme-linked immunosorbent assay for geosmin

Chung, Si Yin; Vercellotti, John R.; Johnsen, Peter B.; Klesius, Phillip H.

doi:10.1021/jf00004a030

Cited by 16 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Results suggest that the enzymes acting on geosmin enantiomers are not very site-specific and that compounds (±)-32 and (±)-33 are likely produced from (+)-geosmin [184]. Furthermore, geosmin's derivatives, argosmin C (30a) and 3-ketogeosmin (32), were synthesized in an attempt to develop an ELISA for geosmin [185]. Results indicated that the binding of the antibody was restricted mainly to the bicyclic structure (A and B rings) of geosmin.…”

Section: Geosmin Derivativesmentioning

confidence: 99%

Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites

Coca-Ruíz

Suárez

Aleu

et al. 2022

Plants

View full text Add to dashboard Cite

The compounds 11,12,13-tri-nor-sesquiterpenes are degraded sesquiterpenoids which have lost the C3 unit of isopropyl or isopropenyl at C-7 of the sesquiterpene skeleton. The irregular C-backbone originates from the oxidative removal of a C3 side chain from the C15 sesquiterpene, which arises from farnesyl diphosphate (FDP). The C12-framework is generated, generally, in all families of sesquiterpenes by oxidative cleavage of the C3 substituent, with the simultaneous introduction of a double bond. This article reviews the isolation, biosynthesis and biological activity of this special class of sesquiterpenes, the 11,12,13-tri-nor-sesquiterpenes.

show abstract

Section: Geosmin Derivativesmentioning

confidence: 99%

Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites

Coca-Ruíz

Suárez

Aleu

et al. 2022

Plants

View full text Add to dashboard Cite

show abstract

“…Hence, the development of novel analytical techniques for express and non-costly GE/MIB detection is an important challenge. Recently, some alternative analytical methods were reported, owing to lower costs and the possibility of rapid GE/MIB detection in potable water; for instance, colorimetry with Tortelli-Jaffe bromine-based reaction [15], enzyme-linked immunosorbent assay (ELISA) for geosmin [16] and indirect competitive immunoassay for MIB [17,18], application of chemical sensors [19] and multisensor arrays, e-nose [20,21], and e-tongue [22] in particular. In the last systems, the chemical sensors with different transduction principles are employed in a combination with multivariate data analysis for GE/MIB analytes identification at levels close to the OTC, thus representing a relevant alternative to costly instrumental techniques for water quality assessment.…”

Section: Ge Mib Ibmentioning

confidence: 99%

Potentiometric E-Tongue System for Geosmin/Isoborneol Presence Monitoring in Drinkable Water

Lvova

Jahatspanian

Mattoso

et al. 2020

Sensors

View full text Add to dashboard Cite

A potentiometric E-tongue system based on low-selective polymeric membrane and chalcogenide-glass electrodes is employed to monitor the taste-and-odor-causing pollutants, geosmin (GE) and 2-methyl-isoborneol (MIB), in drinkable water. The developed approach may permit a low-cost monitoring of these compounds in concentrations near the odor threshold concentrations (OTCs) of 20 ng/L. The experiments demonstrate the success of the E-tongue in combination with partial least squares (PLS) regression technique for the GE/MIB concentration prediction, showing also the possibility to discriminate tap water samples containing these compounds at two concentration levels: the same OTC order from 20 to 100 ng/L and at higher concentrations from 0.25 to 10 mg/L by means of PLS-discriminant analysis (DA) method. Based on the results, developed multisensory system can be considered a promising easy-to-handle tool for express evaluation of GE/MIB species and to provide a timely detection of alarm situations in case of extreme pollution before the drinkable water is delivered to end users.

show abstract

“…Les techniques d'extraction varient et, par conséquent, les limites de détection méthodologiques peuvent être variables. D'autres méthodes comme la colorimétrie (MILLER et al, 1999) et l'immunologie (CHUNG et al, 1991) sont en voie de développement, mais ne donnent pas encore les niveaux de précision requis pour l'analyse de l'eau potable.…”

Section: Méthodes D'analyses Chimiques Des Composés Responsables Des unclassified

Les goûts et les odeurs dans l’eau potable : revue des composés responsables et des techniques de mesure

Proulx¹,

Rodriguez

Sérodes

2010

rseau

View full text Add to dashboard Cite

L’évaluation de la qualité de l’eau potable d’un réseau de distribution est souvent faite en tenant compte des normes physico-chimiques et microbiologiques édictées par les réglementations nationales. L’approche par barrières multiples permet aussi d’assurer aux consommateurs une eau avec une sécurité sanitaire optimale. Cependant, malgré les sommes investies par les municipalités pour se conformer à ces normes, les consommateurs renoncent fréquemment à consommer l’eau du robinet.Ce refus peut être attribué, entre autres, à la qualité organoleptique (goût, odeur) de l’eau distribuée par les réseaux d’aqueduc. Toutefois, cet aspect est peu pris en compte par les législations actuelles et, conséquemment, est peu considéré par les gestionnaires des réseaux d’eau potable. De plus, les méthodes utilisées pour évaluer les molécules responsables des goûts et des odeurs de l’eau distribuée exigent de l’équipement spécialisé et coûteux. Cet article présente une revue de la problématique des composés responsables des goûts et des odeurs. Les aspects concernant les origines de ces composés, les méthodes quantitatives et qualitatives développées jusqu’à présent pour les analyser et la faisabilité d’application desdites méthodes, selon leurs avantages et leurs limites, seront abordés.The assessment of drinking water quality in a distribution system is generally based on physicochemical and microbiological standards set by government regulations. Although municipalities often invest considerable amounts to comply with regulations, an increasing proportion of citizens prefer alternatives to tap water. This situation may be in part explained by the organoleptic quality of distributed water in municipal systems and, in particular, by taste and odours. However, taste and odours are rarely considered as water quality criteria by municipal water managers. Moreover, analytical methods used to analyze molecules related to taste and odours in drinking water require specialized and costly equipment. This article presents the state of the art in terms of taste and odour issues in the drinking water area. The paper focuses on the origins of taste and odours and on the methods (qualitative and quantitative) available for the analysis of the compounds from which they originate. The feasibility of applying these methods to water quality surveillance is discussed, along with their advantages and drawbacks

show abstract

Development of an enzyme-linked immunosorbent assay for geosmin

Cited by 16 publications

References 19 publications

Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites

Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites

Potentiometric E-Tongue System for Geosmin/Isoborneol Presence Monitoring in Drinkable Water

Les goûts et les odeurs dans l’eau potable : revue des composés responsables et des techniques de mesure

Contact Info

Product

Resources

About