Development of an Electrochemical Sensor Conjugated with Molecularly Imprinted Polymers for the Detection of Enrofloxacin

Abstract

An electrochemical sensor was fabricated for the rapid and simple detection of enrofloxacin (EF). Modification of screen-printed gold electrodes (SPE) with molecularly imprinted polymers (MIPs) allowed the detection of enrofloxacin by square wave voltammetry (SWV), measuring the oxidation peak at +0.9 V. The detection principle of molecularly imprinted polymers (MIPs) is based on the formation of binding sites with affinities and specificities comparable with those of natural antibodies. The detection of enrofloxacin showed a linear range of 0.01–0.1 mM with a detection limit LOD of 0.02 mM. The development of a non-imprinted polymer (NIP) control sensor allowed for better and more efficient detection. In addition, the sensor is portable, having the advantage of analyzing and detecting molecules of interest without the need to take the sample to a laboratory.

Efficient Sequential Detection of Two Antibiotics Using a Fiber-Optic Surface Plasmon Resonance Sensor

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A molecularly imprinted polypyrrole electrochemiluminescence sensor based on a novel zinc-based metal–organic framework and chitosan for determination of enrofloxacin

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Dummy template molecularly imprinted polymers as potential sorbents in the separation and purification of active compounds in natural products

“…Molecularly imprinting polymers (MIPs) is a technique for creating polymers that have specific cavities for template compounds so that these cavities can identify template compounds based on their size, structure, and physical-chemical properties. [1][2][3][4] The MIP technique is still being developed today due to the ease of polymer synthesis, low cost, and wide use in many target molecules, as both chemical and biological element identifiers. 5,6 MIPs have been widely used in various fields such as drug development, 7 the food industry, 8,9 forensics, 10 clinical diagnosis, 11,12 and environmental monitoring.…”