Development of an efficient solvent free one-pot Heck reaction catalyzed by novel palladium (II) complex-via green approach

Palladium Nanoparticles Doped on the Chitosan Nanofibers Modified with 2‐Aminobenzaldehyde as a Nanocatalyst in Cross‐Coupling Reactions

“…The most commonly accepted mechanism for Pd‐catalyzed Heck reaction is depicted in Scheme . As shown, the mechanism starts with oxidative addition of the aryl halide (Ar−X) to the Pd (0) to form a Pd (II) complex …”

“…However, it has been found that a large number of reactions occur in the solvent‐free conditions. Solvent‐free reactions have many advantages such as: simple to perform, less pollution, economical and useful in industry …”

A novel imidazolium‐supported palladium–chloroglycine complex: copper‐ and solvent‐free high‐turnover catalysts for the Sonogashira coupling reaction

“…The [Gmim]Cl–Pd(II) complex was synthesized as previously reported and structural conformation available in Supporting information, and the other ionic liquids were synthesized using the literature procedure reported elsewhere …”

“…Their non‐volatile character and thermal stability make the metal complexes potentially attractive alternatives to environmentally unfavorable organic co‐solvents, notably chlorinated hydrocarbons. In particular, they show promise as solvents for the immobilization of transition metal catalysts, Lewis acids and enzymes . As a result of their green credential and potential to enhance reaction rate and selectivities, ionic liquids are finding increasing applications in organic synthesis.…”

Novel Pd-BTP/SiO2as an Effective Heterogeneous Catalyst for Heck Reactions

“…Heck reaction, the arylation and vinylation of alkenes with aryl or vinyl halides, has become a vital tool in chemistry with its ability to synthesize various compounds for uses in polymerization process, UV screening, hydrocarbon process, natural products and active pharmaceutical ingredients [Beletskaya and Cheprakov, 2000;Karthikeyan, et al, 2012; Littke and Fu, 2001;Tessin, et al, 2013]. Palladium-based catalysts are generally used in Heck reactions and those species are highly effective even with less reactive substrates such as aryl chlorides [Iranpoor, et al, 2012;Pagliaro, et al, 2012;Shimizu, et al, 2004].…”