“…PCR testing may have a role, at marginal increased cost, as a prozone check on ACR assays, to guard against this relatively rare analytical issue. 42 But such matters are not the central concern of CKD guidelines intended for non-specialist use. An overwhelming body of evidence is accumulating pointing to the significance of low level protein loss in terms of morbidity and mortality: such data can only be gathered using urinary albumin.…”