Development of an amoxicillin-radix scutellaria extract formulation and evaluation of its pharmacokinetics in pigs
Dandan Yi,
Xuemei Wen,
Wei Xu
et al.
Abstract:Background
A new antibacterial compound powder of amoxicillin (AMO)/Radix Scutellaria extract (RSE) was developed, and its pharmacokinetics were determined in pigs following oral administration.
Results
The MIC ranges of AMO against Escherichia coli, Staphylococcus aureus and Streptococcus were 1–8 μg/mL, 0.5–4 μg/mL and 0.5–64 μg/mL, respectively. The MIC ranges of RSE against E. coli, S. aureus, and Streptococcus were greater than 2.5 mg/mL, 0.15… Show more
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