Development of ambient storable meal for calamity victims and other targets employing radiation processing and evaluation of its nutritional, organoleptic, and safety parameters

Kumar, Sanjeev; Saxena, Sudhanshu; Verma, Jyoti; Gautam, Satyendra

doi:10.1016/j.lwt.2016.01.059

Cited by 15 publications

(16 citation statements)

References 25 publications

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“…Mutation analyses in models including human TK6 lymphoblast cell line at genes tk +/-and hprt + ; and bacterial systems [E. coli MG1655 cells (rpoB gene); and Ames strains (TA 100 and TA 102)] endorsed the genotoxic safety of the SBF product. The product displayed similar antimutagenicity as of fresh samples during Rif R assay, Ames test or mutation assay using TK6 lymphoblast cell line against EMS ans 5-AZ [77]. In Ames test, no mutagenicity induction was observed in high dose (25 kGy) irradiated food 'Kimchi', a Korean food developed and certified as space food [153].…”

Section: Food For Natural Calamity Victims and Other Targetsmentioning

confidence: 84%

“…This assay is advantageous due to its simplicity in deployment, the ability to provide a wide spectrum of forward mutations and low level of spontaneous mutations (approximately 1/10 8 cells) ( Figure 1). It has been extensively used recently to screen the antimutagenic potential of different foods particularly fruits, vegetables and other allied food products at Food Technology Division, Bhabha Atomic Research Centre, Mumbai, India (Figure 2) [20,[50][51][52][53][54][55][75][76][77][78][79]. The assay is better for scoring antimutagenicity over mutagenicity.…”

Section: Rpob-rifampicin Resistance Assaymentioning

confidence: 99%

“…The mutant cells divide and form cellular aggregates (in suspension) through de novo synthesis of nucleotides which can be visualized under an inverted microscope (Figure 1). The result is expressed as the relative number of mutant cells to the total number of seeded cells [54,77].…”

Section: Human Lymphoblast Mutation (Hlm) Assaymentioning

confidence: 99%

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Fruits and Vegetables as Dietary Sources of Antimutagens

Gautam¹,

Saxena²,

Kumar³

2016

J Food Chem Nanotechnol

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Mutation is the process leading to heritable changes in the genetic material of an organism and caused mainly by the external factors, including chemical and physical agents, or can also occur spontaneously due to errors in DNA replication, repair, and recombination. Agents contributing to the mutagenic burden in the environment could be from industrial sources, wide spectrum applications of biocides in the agriculture, and other contaminants. As many of these mutagenic chemicals can induce severe disorders in humans including cancer and a large spectrum of inherited diseases, it is important to detect such mutagenic agents precisely and rapidly, and also look for an approach to combat them. Natural occurring dietary antimutagens primarily from health protective foods such as fruits and vegetables could provide a mechanism to counteract the deleterious effect of these mutagens. The World Health Organization (WHO) indicates that one-third of all cancer deaths are preventable and that diet is closely linked to cancer prevention. These health protective phytochemicals particularly antimutagenic ones could provide an effective solution to these concerns. The current review deals with understanding of the mutagenic events, methods of its analysis and a brief compilation of the existing scientific findings related to the dietary sources having potential to counteract the effects of the mutagenic exposures from different sources. The review would provide an opportunity to look into the science, think about the possible future perspectives and mechanism to translate the outcome of the scientific research for benefits of the mankind.

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Section: Food For Natural Calamity Victims and Other Targetsmentioning

confidence: 84%

Section: Rpob-rifampicin Resistance Assaymentioning

confidence: 99%

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Fruits and Vegetables as Dietary Sources of Antimutagens

Gautam¹,

Saxena²,

Kumar³

2016

J Food Chem Nanotechnol

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“…Foods under study included pulses ( Cajanus cajan , irradiated at D min of 1 kGy), spices ( Coriandrum sativum , Piper nigrum , at 10 kGy), honey (monofloral honey: Pongammia pinnata and Syzygium cumini , at 25 kGy) and a ready‐to‐eat ‘Stuffed Baked Food’ (SBF, at 15 kGy). SBF was conceptualised on an ethnic Indian food and irradiated for eliminating microbial load and prolonged shelf‐life . It was developed under an IAEA‐Coordinated Research Project for natural calamity victims and other targets .…”

Section: Methodsmentioning

confidence: 99%

“…The lymphoblast cell line was also grown in medium fortified with powder prepared from irradiated food. Irradiated foods used in the current study are legume ( Cajanus cajan ), spices ( Coriandrum sativum , Piper nigrum ), honey as well as a ready‐to‐eat baked food termed as Stuffed Baked Food (SBF) . A micronucleus assay using TK6 cells was also performed.…”

Section: Introductionmentioning

confidence: 99%