Development of adsorptive (non-ionic) macroporous resins and their uses in the purification of pharmacologically-active natural products from plant sources

Solanesol: a review of its resources, derivatives, bioactivities, medicinal applications, and biosynthesis

“…Bioactivities of solanesol Solanesol possesses antibacterial, antiviral, antifungal, anticancer, anti-inflammatory, and anti-ulcer activities (Serebryakov and Nigmatov 1990;Khidyrova and Shakhidoyatov 2002;Guo et al 2008;Li and Chase 2010). Chen et al (2007b) indicated that solanesol has significant inhibitory effects on Escherichia coli, Pseudomonas aeruginosa, Staphylococcus Phytochem Rev aureus, and Mycobacterium phlei, but its inhibitory effects on Bacillus subtilis and Bacillus circulans are poor.…”

“…Moreover, solanesol possesses antibacterial, antifungal, antiviral, anticancer, antiinflammatory, and anti-ulcer activities (Serebryakov Fig. 1 The chemical structures of solanesol and solanesol-like substances (SLSs) Phytochem Rev and Nigmatov 1990; Khidyrova and Shakhidoyatov 2002;Guo et al 2008;Li and Chase 2010), and solanesol derivatives have anti-oxidant and antitumour activities, as well as other bioactivities (Enokida et al 2002;Sidorova et al 2002;Zhao et al 2006a;Wang et al 2007;Abdin and Homouda 2008;Srivastava et al 2009;Bentinger et al 2010;Qin et al 2014). Solanesol derivatives can be used for the treatment of cardiovascular disease, osteoporosis, acquired immune deficiency syndrome (AIDS), and wound healing (Srivastava et al 2009;Hu and Wang 2011;Wang et al 2013a, b).…”

Chemical investigation and antimicrobial properties of mastic water and its major constituents

“…On the other hand, the new extraction procedure was based on the property of the XAD4 resin to absorb low molecular weight organic hydrophobic molecules from an aqueous medium and then to desorb them when treated with an organic solvent such as diethyl ether. This method has been previously successfully applied in the case of wine volatiles (Ferreira, Ortiän, Escudero, Pez, & Cacho, 2002), grape distillates (Lelis et al, 2008), beer (Pothou, Melliou, Magiatis, Skaltsounis, & Liouni, 2009) and has the advantage that it can be used for the extraction of large-scale quantities (Li & Chase, 2010).…”

Purification of baicalin and wogonoside from Scutellaria baicalensis extracts by macroporous resin adsorption chromatography

“…In view of the important pharmacological properties and the difficulties connected with existing purification methods, the application of low-cost technology to obtain baicalin and wogonoside from S. baicalensis is a rational strategy. Recently, macroporous resin chromatography has become increasingly used for separating bioactive components from crude extracts of herbal raw materials, attributing to its unique adsorption properties and advantages including high adsorption capacity, good stability, low operational cost, less solvent consumption and easy regeneration [18]. Resins have been widely used for the enrichment and separation of some secondary metabolites including flavonoids [19][20][21][22][23].…”