DEVELOPMENT OF ABSORBABLE SUTURES FROM CHITIN11Poster presentation at the Second World Congress on Biomaterials, 10th Annual Meeting of the Society for Biomaterials, Washington, D. C., April 27-May 1, 1984.

Nakajima, Mitsutoshi; Atsumi, Kazuhiko; Kifune, Koji

doi:10.1016/b978-0-12-780950-2.50031-9

Cited by 22 publications

(2 citation statements)

References 3 publications

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“…301 Chitin filaments were proposed as absorbable surgical sutures even though the halogenated solvents act as plasticizers. 302,303 The trichloroacetic-chloral hydrate-dichloroethane (4:4:2) solvent system was found to dissolve chitin, but the resulting filaments had no substantially improved mechanical properties. 304,305 Moreover, implementation of these spin systems represents a problem: trichloroacetic and dichloroacetic acids are corrosive and degrade chitin even after a short exposure, chlorohydrocarbons are environmentally unacceptable, formic acid can act as a sensitizer, and fluorinated alcohols and ketones are toxic.…”

Section: Early Approaches To Fiber Productionmentioning

confidence: 99%

Chitosan Chemistry and Pharmaceutical Perspectives

et al. 2004

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Section: Early Approaches To Fiber Productionmentioning

confidence: 99%

Chitosan Chemistry and Pharmaceutical Perspectives

et al. 2004

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“…33 The viscosity of the polymer solution can be controlled via the chitin pretreatment (up to 2 h showed added effects), LiCl concentration (optimum 5-9%), chitin concentration (optimum spinnable solution with 5-9% chitin) and temperature. Chitin purified from red crabs was made into fibres by Nakajima et al 34 via dissolution in an amide-LiCl system. Filaments of 5 mm diameter were spun from a spinneret of 0?05 mm diameter, using a butyl alcohol coagulant.…”

Section: Chitin and Chitosanmentioning

confidence: 99%

Fibre-reinforced hydrogels with high optical transparency

Maranchi

Trexler

Guo

et al. 2014

International Materials Reviews

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Fibre-reinforced hydrogels with high optical transparency are an emerging composite material with great promise to enable new applications, such as a transparent wound dressing with custom tuned mechanical properties that provides desirable mechanical and physical properties along with optical clarity for facile wound inspection. Stand-alone hydrogels are an important class of materials comprising a cross-linked polymer network surrounded by a water matrix. However, their mechanical properties are typically very modest compared with other materials. While significant research is going on in parallel in the fields of hydrogels and reinforcement fibres, researchers are only starting to scratch the surface of the possibilities of combining the two. This report provides a review of natural and synthetic reinforcement fibre research with special emphasis placed on nanofibres. These provide the added benefit of transparency by being much smaller than the wavelength of visible light. A review of hydrogel materials is also presented. The mechanical properties, optical properties and biological functionality of hydrogel systems are also described. Ocular, load-bearing tissue, wound management and sensing/ device applications are all discussed. Transparent fibre-reinforced hydrogels provide a compelling potential solution to enable advanced functionality, in particular in the wound care and optical application areas.

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Fiber-matrix interface studies on bioabsorbable composite materials for internal fixation of bone fractures. I. Raw material evaluation and measurement of fiber?matrix interfacial adhesion

Slivka

Chu

Adisaputro

1997

J. Biomed. Mater. Res.

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The objective of this study was to characterize and evaluate the performance of various fiber-matrix composite systems by studying the mechanical, thermal, and physical properties of the fiber and matrix components, and by studying the fiber-matrix interface adhesion strength using both microbond and fragmentation methods. The composites studies were poly(L-lactic acid) (PLLA) matrix reinforced with continuous fibers of either nonabsorbable AS4 carbon (C), absorbable calcium phosphate (CaP), poly(glycolic acid) (PGA), or chitin. Carbon and CaP single fibers had high Young's moduli and failed in a brittle manner. PGA and chitin single fibers had relatively lower Young's moduli and relatively higher ductility. Upon in vitro hydrolysis, CaP fibers retained 17% of their tensile strength and 39% of their Young's modulus after 12 h, PCA fibers retained 10% of their tensile strength and 52% of their Young's modulus after 16 days, and chitin fibers retained 87% of their tensile strength and 130% of their Young's modulus after 25 days. PLLA films had much lower strength and Young's moduli, but much higher ductility relative to the single fibers. Using the microbond method, the initial fiber-matrix interfacial shear strength (IFSS) of C/PLLA and CaP/PLLA microcomposites was 33.9 and 12.6 MPa, respectively. Upon in vitro hydrolysis, C/PLLA retained 49% of IFSS after 15 days and CaP/PLLA retained 46% of IFSS after 6 h. Using a fiber fragmentation method, the initial IFSS of C/PLLA, CaP/PLLA, and chitin/ PLLA was 22.2, 15.6, and 28.3 MPa, respectively. The performance of carbon fibers and C/PLLA composites was superior to the other fibers and fiber/PLLA systems, but the carbon fiber was nonabsorbable. CaP had the most suitable modulus of the absorbable fibers for fixing cortical bone fracture, but its rapid deterioration of mechanical properties and loss of IFSS limits its use. PGA and chitin fibers had suitable mechanical properties and their retention for fixing cancellous bone fractures, but likely had insufficient stiffness for applications such as bone plates for fixing cortical bone fractures.

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DEVELOPMENT OF ABSORBABLE SUTURES FROM CHITIN11Poster presentation at the Second World Congress on Biomaterials, 10th Annual Meeting of the Society for Biomaterials, Washington, D. C., April 27-May 1, 1984.

Cited by 22 publications

References 3 publications

Chitosan Chemistry and Pharmaceutical Perspectives

Chitosan Chemistry and Pharmaceutical Perspectives

Fibre-reinforced hydrogels with high optical transparency

Fiber-matrix interface studies on bioabsorbable composite materials for internal fixation of bone fractures. I. Raw material evaluation and measurement of fiber?matrix interfacial adhesion

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