Development of abscisic acid receptor agonists/antagonists and their application prospect in agriculture: An overview

Synthesis, Plant Growth Regulatory Activity, and Transcriptome Analysis of Novel Opabactin Analogs

“…The crystal structure of compound 4h is depicted in Figure 3. Its crystal data are as follows: space group P 21 , α = 90°, β = 95.4150(10)°, γ = 90°, V = 1104.50(3) Å 3 , Z = 2, density = 1.270 g/cm 3 , absorption coefficient = 0.732 mm −1 , F(000) = 448.0, data completeness = 1.54/0.84, maximum theta angle = 68.153, and R (reflections) = 0.0306 (3328). The crystallographic data for compound 4h have been archived with the Cambridge Crystallographic Data Center under Supporting Information No.…”

“…Therefore, there is an urgent need to develop new strategies to effectively mitigate the adverse effects of drought stress on agricultural productivity. One approach to alleviate the impact of drought on crop yields involves using chemicals to reduce transpiration from the leaf surface during the early stages of plant exposure to drought stress. , The goal is to increase the plant’s water reserves for normal growth and development in the future. Specific receptors for abscisic acid (ABA), a plant hormone (Figure ), have emerged as promising targets for these antitranspirants. − When there is a water shortage, the endogenous ABA levels increase rapidly, activating the ABA signaling pathway, which leads to stomatal closure and reduced water loss through transpiration. , Additionally, this activation induces the expression of various stress-responsive genes involved in processes such as osmotic regulation, dehydration tolerance, and the management of reactive oxygen species. − Researches indicate that applying exogenous ABA significantly improves crop productivity during drought conditions. , However, the practical use of natural ABA in agriculture is limited due to several main drawbacks associated with its use as a plant growth regulator.…”

“…One approach to alleviate the impact of drought on crop yields involves using chemicals to reduce transpiration from the leaf surface during the early stages of plant exposure to drought stress. 2,3 The goal is to increase the plant's water reserves for normal growth and development in the future. Specific receptors for abscisic acid (ABA), a plant hormone (Figure 1), have emerged as promising targets for these antitranspirants.…”

Synthesis of constrained bicycloalkanes through bibase-promoted brook rearrangement/radical-polar crossover cyclization

“…Constrained cycloalkanes, such as cyclopropanes, cyclobutanes, oxetanes and azetidines subunits, have received huge attention for more than 100 years not only due to their broad reactivity profile to improve drug's potency and biological activity, but also due to the opportunity to utilize these fragments as highly reactive building blocks in organic synthesis, 1 and even cyclopropanes and cyclobutane units can easily undergo opening reactions because of their high ring strain energies ( ca. 27.5 and 26.7 kcal.mol −1 ).…”