Development of a ZnCdS@ZnS quantum dots–based label-free electrochemiluminescence immunosensor for sensitive determination of aflatoxin B1 in lotus seed

Sun, Chaonan; Liao, Xiaofang; Jia, Boyu; Shi, Linchun; Zhang, Dingkun; Wang, Ruilin; Zhou, Lidong; Kong, Weijun

doi:10.1007/s00604-020-4179-x

Cited by 31 publications

(13 citation statements)

References 38 publications

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“…The signal of "signal-off" ECL biosensors is inversely proportional to concentration of analyte determination. For instance, signal of competitive immunoassay ECL by NiFe 2 O 4 as carrier for Ru(bpy) 3 2 + luminophore was negative correlation with concentration of ZEN [118]. As shown in Figure 7A, peptide-loaded NiFe 2 O 4 @Ru(bpy) 3 2 + probes simulated ZEN combine with ZEN-Ab, resulting the ECL signal enhanced.…”

Section: "Signal-off" Ecl Biosensors For Mycotoxinsmentioning

confidence: 93%

Mycotoxins Detection Based on Electrochemical Approaches

et al. 2021

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Electrochemical biosensors have attracted much attention in mycotoxin bioanalysis. In this review, three electrochemical biosensor technologies for mycotoxins were reviewed, including general electrochemistry, photoelectrochemistry, and electrochemiluminescence. Based on the classification of multiple electrochemical detection methods, the design schemes, recognition mechanism and probe materials were described in detail. Moreover, the characteristics and limitations of these electrochemical biosensors were summarized. The challenges and future trends of electrochemical biosensor development in mycotoxin bioanalysis were also briefly discussed in the end. This review is expected to provide some inspirations for point-of-care testing in electrochemical sensors for mycotoxins and further electrochemical analysis application.

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Section: "Signal-off" Ecl Biosensors For Mycotoxinsmentioning

confidence: 93%

Mycotoxins Detection Based on Electrochemical Approaches

et al. 2021

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“…This ECL aptasensor showed satisfactory recoveries of OTA in beer and wine with the LOD of 12 pmol/L. Other researchers developed a label-free ZnCdS@ZnS QDs-based ECL immunosensor for AFB1 detection in lotus seed [ 92 ]. Quantum dots and Nafion were assembled on Au electrode surface as ECL signal probes and anti-AFB1 antibodies were coupled as the capturing element.…”

Section: Rapid Detection Strategiesmentioning

confidence: 99%

Recent advances in immunoassays and biosensors for mycotoxins detection in feedstuffs and foods

Yang

Wang

et al. 2021

J Animal Sci Biotechnol

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Mycotoxins are secondary metabolites produced by fungus. Many mycotoxin species are highly toxic and are frequently found in cereals and feedstuffs. So, powerful detection methods are vital and effective ways to prevent feed contamination. Traditional detection methods can no longer meet the needs of massive, real-time, simple, and fast mycotoxin monitoring. Rapid detection methods based on advanced material and sensor technology are the future trend. In this review, we highlight recent progress of mycotoxin rapid detection strategies in feedstuffs and foods, especially for simultaneous multiplex mycotoxin determination. Immunoassays, biosensors, and the prominent roles of nanomaterials are introduced. The principles of different types of recognition and signal transduction are explained, and the merits and pitfalls of these methods are compared. Furthermore, limitations and challenges of existing rapid sensing strategies and perspectives of future research are discussed.

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“…Besides these three interactions, the label-free method has been widely used in ECLIA [12][13][14][15][16][17][18][19][20][21]. In labelfree ECLIA, luminophore is not labelled in the antibody but is present in the system as an added reagent.…”

Section: Sandwich Interactionmentioning

confidence: 99%

“…Sun et al [14] studied the use of Zinc Cadmium Sulfide/Zinc Sulfide quantum dots (ZnCdS@ZnS QDs) as a label in the detection of aflatoxin B1. ZnCdS QDs capped with ZnS and assembled with Nafionimmobilized Au electrode.…”

Section: Nanomaterialsmentioning

confidence: 99%

Electrogenerated Chemiluminescence for Immunoassay Applications

et al. 2021

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Electrogenerated chemiluminescence (ECL) has recently become one of the most prominent and well-established transducers for immunoassay techniques. ECL relates a luminophore concentration in solution with the emission of light triggered by an electrochemical stimulus. ECL immunoassay (ECLIA) performance depends on the parameters of its light generation, including the luminophore, the species that emit light called labels in ECLIA; co-reactants, which are added reagents that support the luminophore to undergo the excited state; electrodes, which are the place for the ECL reactions to take place; and the format of the immunoassay. This review discusses the behaviour of ECLIA parameters, the required instrumentations, and some important examples of detections based on ECLIA.

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Development of a ZnCdS@ZnS quantum dots–based label-free electrochemiluminescence immunosensor for sensitive determination of aflatoxin B1 in lotus seed

Cited by 31 publications

References 38 publications

Mycotoxins Detection Based on Electrochemical Approaches

Mycotoxins Detection Based on Electrochemical Approaches

Recent advances in immunoassays and biosensors for mycotoxins detection in feedstuffs and foods

Electrogenerated Chemiluminescence for Immunoassay Applications

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