Development of a Wine Metabolomics Approach for the Authenticity Assessment of Selected Greek Red Wines

Abstract

Wine metabolomics constitutes a powerful discipline towards wine authenticity assessment through the simultaneous exploration of multiple classes of compounds in the wine matrix. Over the last decades, wines from autochthonous Greek grape varieties have become increasingly popular among wine connoisseurs, attracting great interest for their authentication and chemical characterization. In this work, 46 red wine samples from Agiorgitiko and Xinomavro grape varieties were collected from wineries in two important winemaking regions of Greece during two consecutive vintages and analyzed using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QToF-MS). A targeted metabolomics methodology was developed, including the determination and quantification of 28 phenolic compounds from different classes (hydroxycinnamic acids, hydroxybenzoic acids, stilbenes and flavonoids). Moreover, 86 compounds were detected and tentatively identified via a robust suspect screening workflow using an in-house database of 420 wine related compounds. Supervised chemometric techniques were employed to build an accurate and robust model to discriminate between two varieties.

Global Metabolome of Palmer Amaranth (Amaranthus palmeri) Populations Highlights the Specificity and Inducibility of Phytochemical Responses to Abiotic Stress

“…In addition to phenylpropanoids and terpenoids, four nitrogenous glycosides (vicine, hypoxanthine pentoside, indoxyl hexopyranoside derivative (accurate mass_retention time: 427.148_9.13), and indole glycoside derivative (367.127_10.02) and two jasmonic acid-derived glycosides (tuberonic acid hexoside and isocucurbic acid hexoside) were also identified , [Table S3].…”

Metabolite profiles across populations of Palmer amaranth (Amaranthus palmeri) highlight the specificity and inducibility of phytochemical response to glyphosate stress

“…In addition to phenylpropanoids and terpenoids, four nitrogenous glycosides (vicine, hypoxanthine pentoside, indoxyl hexopyranoside_427.148_9.13, and indole glycoside_367.127_10.02) and two jasmonic acid-derived glycosides (tuberonic acid hexoside, and isocucurbic acid hexoside) were also identified (Rizzello et al, 2016; Tzachristas et al, 2021) [Table S3].…”

Emerging trends and applications of metabolomics in food science and nutrition

“…232 The identification of beer origin was attempted using some potential markers, including furan-2-ylmethanol,-propane-1,2,3-triol, 2 H -furan-5-one, furan-2-carbaldehyde, maltol, proline,-5-oxo proline, adenosine, maltoxazine, propionic, lactic, ketobutyric, maleic, isohumulinone, and anhydrohexose. A specific sort or brand of Trappist beer can be authenticated using LC-MS-profiling in conjunction with MVDA 233 (Table 4).…”