Development of a Synthetic Synovial Fluid for Tribological Testing

Bortel, Emely; Charbonnier, Baptiste; Heuberger, Roman

doi:10.3390/lubricants3040664

Cited by 68 publications

(58 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The same wear experiments were repeated 6 times in passivating environment of phosphate buffered saline (PBS) solution and artificial synovial environment. Hyaluronic acid (HA) at the concentration of 3 g/L and bovine serum albumin (BSA) at the concentration of 19 g/L were dissolved in PBS solution [19]. A custom design bath was manufactured from an ultra-high-molecular-weight-polyethylene cylinder to securely hold the specimen and to be mounted on the tester stage.…”

Section: Wear Experimentsmentioning

confidence: 99%

Sliding Contact Wear Damage of EBM built Ti6Al4V: Influence of Process Induced Anisotropic Microstructure

Ryu

Shrestha

Manogharan

et al. 2018

Metals

View full text Add to dashboard Cite

Process-induced directional microstructure is identified as one of the key factors of anisotropic mechanical properties. This directional property significantly affects surface contact fatigue and corrosion of electron beam melting (EBM) built biomedical implants. In the current study, material removal on EBM built titanium (Ti6Al4V) subjected to reciprocating motion of commercially pure titanium spherical slider is investigated to identify the influence of the process-induced layered structure and environments on wear damage. Specimens developed by two different build orientations are mechanically stimulated using different sliding directions with nominally elastic normal load in dry, passivating, and synovial environments. It was noticed that EBM orientation significantly changes wear behavior in ambient environment. Wear resistance of mill-annealed Ti6Al4V was improved in passivating environment. Implications to improve useful life of orthopedic implants are discussed.

show abstract

Section: Wear Experimentsmentioning

confidence: 99%

Sliding Contact Wear Damage of EBM built Ti6Al4V: Influence of Process Induced Anisotropic Microstructure

Ryu

Shrestha

Manogharan

et al. 2018

Metals

View full text Add to dashboard Cite

show abstract

“…Foetal bovine serum (FBS) was employed as the model synovial fluid [40,41]. The applied load, sliding speed and total sliding distance were 10 N, 50 mm/s and 1000 m, respectively.…”

Section: Tribological Measurements: Pin-on-disk Tribometry and Dynamimentioning

confidence: 99%

A Preliminary Study to Enhance the Tribological Performance of CoCrMo Alloy by Fibre Laser Remelting for Articular Joint Implant Applications

2018

View full text Add to dashboard Cite

Abstract:CoCrMo alloy has long been used as a pairing femoral head material for articular joint implant applications because of its biocompatibility and reliable tribological performance. However, friction and wear issues are still present for CoCrMo (metal)/CoCrMo (metal) or CoCrMo (metal)/ultrahigh molecular weight polyethylene (UHMWPE) (plastic) pairs in clinical observations. The particulate wear debris generated from the worn surfaces of CoCrMo or UHMWPE can pose a severe threat to human tissues, eventually resulting in the failure of implants and the need for revision surgeries. As a result, a further improvement in tribological properties of this alloy is still needed, and it is of great interest to both the implant manufacturers and clinical surgeons. In this study, the surface of CoCrMo alloy was laser-treated by a fibre laser system in an open-air condition (i.e., no gas chamber required). The CoCrMo surfaces before and after laser remelting were analysed and characterised by a range of mechanical tests (i.e., surface roughness measurement and Vickers micro-hardness test) and microstructural analysis (i.e., XRD phase detection). The tribological properties were assessed by pin-on-disk tribometry and dynamic light scattering (DLS). Our results indicate that the laser-treated surfaces demonstrated a friction-reducing effect for all the tribopairs (i.e., CoCrMo against CoCrMo and CoCrMo against UHHMWPE) and enhanced wear resistance for the CoCrMo/CoCrMo pair. Such beneficial effects are chiefly attributable to the presence of the laser-formed hard coating on the surface. Laser remelting possesses several competitive advantages of being a clean, non-contact, fast, highly accurate and automated process compared to other surface coating methods. The promising results of this study point to the possibility that laser remelting can be a practical and effective surface modification technique to further improve the tribological performance of CoCr-based orthopaedic implants.

show abstract

“…Authors from Portugal investigated the friction of human skin against different fabrics for medicinal use [3], a team from the US presents a quantitative analysis of retrieved glenoid liners [4] and authors from Switzerland and Germany report on the development of a synthetic synovial fluid for tribological testing of joint prostheses [5]. Friction between the human skin and textiles is a critical factor in the formation of skin injuries which are caused if the loads and shear forces are high enough and/or take place over long periods of time.…”

mentioning

confidence: 99%

“…Authors from Switzerland and Germany address the development of a synthetic synovial fluid for preclinical wear tests predicting the in vivo performance of joint prostheses [5]. Usually, wear tests of joint prostheses are performed using various bovine sera, with different protein concentrations and compositions.…”

mentioning

confidence: 99%

Editorial: Friction and Lubricants Related to Human Bodies

Gebeshuber

Aken

2017

Lubricants

View full text Add to dashboard Cite

Biolubrication plays a crucial role in assisting the sliding contacts in many organs in the human body. Notable examples are the joints, the skin surface, the eye, the mouth and gastrointestinal tract, the lungs and the red blood cells. In all cases, reduced lubrication leads to increased friction and adhesion between the surfaces in contact, which may lead to the surfaces becoming stuck and damaged, ultimately leading to irritation, pain and trauma. Over the past few decades, major advancements have been achieved in the accumulation of knowledge on the subject.Joint lubrication has been shown to involve a complex and probably adaptive set of lubrication mechanisms involving the smoothness of the cartilage lining of the bone surfaces, the properties of the synovial fluid, which is a lubricating hydrogel of collagen fibrils, hyaluronic acid, glycoproteins (lubricin) and water, and a weeping mechanism by which joint pressure releases synovial fluid into the interspacing liquid film separating the cartilage surfaces.The lubrication of epidermal surfaces such as the skin, eye, mouth, lung and gastrointestinal tract follows different mechanisms. The relatively dry surface of the skin and hair is protected and lubricated by a thin coating of sebum in which moisture plays a critical role. On the one hand, moisture reduces the sliding resistance by providing suppleness, elasticity, plasticity, flexibility and softness to the deeper layers of the skin, but on the other, it increases the adhesive properties, friction and microbial proliferation of the outer surface. Loss of skin surface lubricity can lead to unpleasant sensations of contact with clothes, fabrics and solid surfaces, and can lead to uncomfortable stickiness, irritation, trauma and wounds such as decubitus. The naturally moist mucosal surfaces of the eyes, mouth, lung, gastrointestinal tract and vulva are kept in a lubricated state by specific biolubricants, i.e., glycoproteins (mucins), (phospho-)lipids and water. Insufficient lubrication can lead to various discomforting and clinical conditions such as the eyeball sticking to the eyelid or to contact lenses, xerostomia (dry mouth syndrome, due to a reduced salivary flow or quality, resulting in difficulty in swallowing and speaking), pleuric rub caused by various lung diseases, difficulty in sexual penetration, bowel irritation and trauma which can ultimately lead to cancer development. A special aspect of the biolubrication of the mouth is in the way it affects sensory and texture perception. The effect is strongly related to the perception of smoothness, creaminess and the opposite of roughness and astringency, which probably have the biological function to test the quality of the food material for the way it affects the lubrication of the mucosal lining of the alimentary tract, giving feedback to food preference and eating behavior (speed, subsequent food selection during a meal).In relation to the various symptoms of imparted lubrication, various studies are focused on specific lubricants and moisturiz...

show abstract

Development of a Synthetic Synovial Fluid for Tribological Testing

Cited by 68 publications

References 63 publications

Sliding Contact Wear Damage of EBM built Ti6Al4V: Influence of Process Induced Anisotropic Microstructure

Sliding Contact Wear Damage of EBM built Ti6Al4V: Influence of Process Induced Anisotropic Microstructure

A Preliminary Study to Enhance the Tribological Performance of CoCrMo Alloy by Fibre Laser Remelting for Articular Joint Implant Applications

Editorial: Friction and Lubricants Related to Human Bodies

Contact Info

Product

Resources

About