Development of a surfactant‐assisted dispersive solid phase extraction using deep eutectic solvent to extract four tetracycline antibiotics residues in milk samples

Abstract

In this study, a new floating dispersive solid phase extraction method based on deep eutectic solvents has been developed in a home-made extraction device for the extraction of four tetracycline antibiotics from milk samples. In this approach, the sorbent (activated carbon) was dispersed in whole parts of solution with the aid of air stream and floated on top of the solution with the aid of the surfactant (lauryl betaine) and air bubbles. After collection of the sorbent, the adsorbed analytes were eluted with tetrabutyl ammonium chloride-propionic acid deep eutectic solvent under sonication. In this method, there was no need of organic dispersive and extraction solvents and the used sorbent was collected on top of the solution and collected without centrifugation. The validation parameters showed that low limits of detection (0.1-0.3 μg/kg) and quantification (0.6-1.0 μg/kg), acceptable enrichment factors (52-60), efficient extraction recoveries (80-91%), and satisfactory relative standard deviations (≤9.8%) were obtained. Eventually, the method was successfully applied on different milk samples and tetracycline was determined in them.

In‐situ sorbent formation for the extraction of pesticides from honey

“…DSPE is a powerful and efficient extraction procedure in which the analytes dissolved in the sample solution are adsorbed onto the surface of a few amounts of an adsorbent. Commercial adsorbents like octadecylsilane [13], primary secondary [14], silica gel [15], and activated carbon [16] are frequently used sorbents in DSPE. However, in recent years, many attempts have been done towards the development of DSPE methods with new sorbents.…”

Evaluation of three sorbent‐phase extraction techniques based on hyper‐crosslinked polymer for the extraction of five endocrine disrupters in water

“…DSPE is another novel pattern of SPE [16]. At present, different types of sorbents [17][18][19] have been performed to exploit their potential for the DSPE technique. For example, Su et al [20] prepared the cadmium(II)-based metalorganic framework for the DSPE procedure of brominated flame retardants from the water samples, under optimized condition, excellent recoveries (83.9-102.2%) were reached with RSDs lower than 5.57%.…”