Development of a Surface Ionization Mass Spectrometry Method for the Highly Sensitive and Highly Selective Analysis of Morphine in Biofluid

Interpol Review of Drug Analysis 2019-2022

“…2019 novel and sensitive sensor for morphine based on electrochemically synthesized poly(p-aminobenzenesulfonicacid)/reduced grapheneoxide (poly(p-ABSA)/RGO) composite modified glassy carbon electrode [ 212 ]; nine step method to synthesize morphine from o-vanillin [ 213 ]; immunochromatographic lateral flow strip with gold nanoparticles labeling was developed for monitoring of morphine [ 214 ]; electrochemical sensor for detection of morphine [ 215 ]; 2020 Review of electrochemical detection methods of differeent moodified electrodes for deteection of morphine [ 216 ]; synthesis and use of poly(cetyltrimethylammoniumbromide)/graphene oxide (poly(CTAB)/GO) composite as novel sensor for morphine detection [ 217 ]; sensor for determination of morphine and diclofenac via differential pulse voltammetric, cyclic voltammetric, and chronoamperometry [ 218 ]; fluorescence immunoassay method for detection of morphine [ 219 ]; 2021 surface ionization mass spectrometry method for the direct detection and analysis of morphine [ 220 ]; a quantitative lateral flow immunoassay instrument that uses magnetic resistance sensors for quantitative measurement of morphine [ 221 ]; comparison of two different sensing platforms (electrochemical impedance spectroscopy and a quartz crystal microbalance) for the detection of morphine [ 222 ]; evaluation of the use of plant extracts and herbal products as a SPME sorbet for use with RP-HPLC and LC-MS/MS for detection of Morphine and Codeine [ 223 ]; electrochemical sensor for DPV determination of morphine [ 224 ]; utilization of a gas-phase chloride attachment with IMS for selective detection of morphine in a morphine/codeine mixture [ 225 ]; N,Cl-doped deep eutectic solvents-based carbon dots as a selective fluorescent probe for determination of morphine in food [ 226 ]; electrochemical sensor for detection of morphine in drug samples [ 227 ]; 2022 electrochemical sensor for simultaneous detection of Diclofenac and Morphine [ 228 ]; sensor for detection of morphine [ 229 , 230 ]; methodology to isolate morphine from opium and heroin (deacetylated to morphine) for isotopic analysis and regional analysis of submissions from Mexico, South America, Southwest Asia, and Southeast Asia [ 231 ]; electrochemical sensors for detection of morphine in unprocessed coffee and milk [ 232 ].…”

Determination of kinetic characteristics of molecule thermodesorption on the surface of oxidated molybdenum

“…In this work, to determine the kinetic characteristics of thermodesorption of C 9 H 7 N + CH 3 radical with m / z 144 in the form of ions and neutral particles during adsorption of morphine molecules on the Mo x O y surface we used the voltage modulation method (VMM). Morphine molecules were selected as an object of studying the non‐stationary processes of organic compound by the VVM since their SI on the surface of oxidized tungsten was well studied under stationary conditions 6–10 . In addition, morphine was studied by mass spectrometric methods such as electron ionization (EI), electrospray ionization (ESI), chemical ionization (CI), and other ionization methods in vacuum and in air 11–20 .…”

Mass-spectrometric studies of kinetic characteristics of codeine molecule thermodesorption by non-stationary surface ionization method

“…[9][10][11] Moreover, codeine was studied by the mass spectrometric and chromatography-mass spectrometric methods, such as electron ionization (EI), electrospray ionization (ESI), chemical ionization (CI) and other ionization methods in vacuum and in air. [12][13][14][15][16][17][18][19][20] In this work, the kinetic characteristics of thermodesorption of radicals in the form of ions and neutral particles during the codeine molecule adsorption on the W x O y surface have been determined by the VMM.…”

“…9–11 Moreover, codeine was studied by the mass spectrometric and chromatography–mass spectrometric methods, such as electron ionization (EI), electrospray ionization (ESI), chemical ionization (CI) and other ionization methods in vacuum and in air. 12–20…”