Development of a sarcoma in a surgical scar

Sherlock, David; Rickards, Hugh; Gardecki, T.; Hamer, J. D.

doi:10.1136/pgmj.63.746.1097

Cited by 26 publications

(4 citation statements)

References 4 publications

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“…Among the reconstruction techniques using autologous bone, the flap positioned subcutaneously in the abdominal cavity [2,20,23,38] requires a second surgical wound. This aspect, seemingly marginal, should not be underestimated because the onset of benign [9,18,32] or malignant [13,16,21,30,31,34,35,39] primary tumours from the surgical abdominal or thoracic scar is well-documented, both many years after surgery for benign lesions and after a few months for malignant ones. On the other hand, if the bone flap is kept in the subgaleal space [12,19,25] there may be undesired subcutaneous blood collections, but mainly a smaller skin surface available for brain swelling, since it is already employed in containing the craniotomy flap.…”

Section: Discussionmentioning

confidence: 99%

Ethylene oxide sterilization of autologous bone flaps following decompressive craniectomy

Missori

Polli

Rastelli

et al. 2003

Acta Neurochirurgica

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Section: Discussionmentioning

confidence: 99%

Ethylene oxide sterilization of autologous bone flaps following decompressive craniectomy

Missori

Polli

Rastelli

et al. 2003

Acta Neurochirurgica

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“…It is well known that scars are a predisposing factor in the development of cutaneous malignancy and there have been several previous reports of DFSP occurring in scars of varying aetiology [25][26][27][28][29]. The development of malignancy in vaccination scars is well recognised and, specifically, several previous case reports have documented the occurrence of DFSP in this setting [2,[4][5][6][7].…”

Section: Aetiologymentioning

confidence: 95%

“…These include the development of DFSP at sites of trauma ranging from 'vaccination to bayonet wound' [2], such as surgical scars [25][26][27], burn scars [28,29], sites of prior immunisation [4][5][6][7] and therapeutic irradiation [12,30]. In addition, increased frequency of trauma to the hands and feet is thought to account for the higher incidence of acrally occurring DFSP in children and adolescents compared to adults [12].…”

Section: Aetiologymentioning

confidence: 99%

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Dermatofibrosarcoma Protuberans Arising in a Decorative Tattoo

Baker

O'Dowd²,

Khan

2000

Sarcoma

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Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive cutaneous tumour of intermediate grade malignancy. A number of reports have linked local trauma of varying aetiology with the later development of DFSP. In addition, a variety of skin disorders and, in rare cases, cutaneous tumours, have been described in association with decorative tattoos. This is often associated with delayed diagnosis. We report the first case of DFSP arising in a tattoo and discuss the available evidence for a causative link between DFSP and local trauma of this nature.

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The etiology of acute hepatitis superimposed upon previously unrecognized asymptomatic HBsAg carriers

et al. 1989

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To study the etiology of acute hepatitis superimposed upon previously unrecognized asymptomatic HBsAg carriers, paired sera were collected in acute and convalescence phases for measurement of HBeAg, anti-HBe, hepatitis B virus DNA and anti-delta from 76 adult patients with acute hepatitis who were HBsAg positive but IgM anti-HBc negative or positive only at low titer. None of them were IgM anti-hepatitis A virus positive on admission. Of the 34 patients who were HBeAg positive initially, two (5.9%) were diagnosed as having delta superinfection, and another two (5.9%) were suspected to have non-A, non-B virus superinfection because of a transient decrease of serum hepatitis B virus DNA. The remaining 30 (88.2%) cases were hepatitis B virus DNA negative with or without anti-HBe seroconversion on follow-up. The episodes of acute hepatitis in these cases may represent "immune clearance of HBeAg" or "immune clearance of hepatitis B virus with delayed anti-HBe seroconversion," respectively, in the natural course of chronic hepatitis B virus infection. Of the patients who were anti-HBe positive initially, 23 (54.8%) were diagnosed as having delta superinfection, including eight with de novo seroconversion of anti-delta and 15 with a rising titer of anti-delta; 10 (23.8%) were positive for hepatitis B virus DNA and were considered as reactivation of hepatitis B virus, and the other nine (21.4%) were suspected as having non-A, non-B virus superinfection.(ABSTRACT TRUNCATED AT 250 WORDS)

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Development of a sarcoma in a surgical scar

Cited by 26 publications

References 4 publications

Ethylene oxide sterilization of autologous bone flaps following decompressive craniectomy

Ethylene oxide sterilization of autologous bone flaps following decompressive craniectomy

Dermatofibrosarcoma Protuberans Arising in a Decorative Tattoo

The etiology of acute hepatitis superimposed upon previously unrecognized asymptomatic HBsAg carriers

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