Development of a rapid method for assessing the efficacy of antibacterial photocatalytic coatings

Scimone, Antony; Redfern, James; Patiphatpanya, Panudda; Thongtem, Titipun; Ratova, Marina; Kelly, Peter

doi:10.1016/j.talanta.2020.122009

Cited by 6 publications

(3 citation statements)

References 83 publications

(95 reference statements)

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“…Microbial contamination and biofilm formation on medical devices are one of the major threats associated with biomaterial-assisted complications. Biofilm formation on the surface of medical implants is very difficult to prevent . Lack of hygienic handling and the nature of the implant can be the reasons for these infections.…”

Section: Methods For Developing Infection-resistant Surface Modificat...mentioning

confidence: 99%

“…Biofilm formation on the surface of medical implants is very difficult to prevent. 39 Lack of hygienic handling and the nature of the implant can be the reasons for these infections. Preventing the microbial colonization and effective killing of the microbes are the solutions to controlling the infection.…”

Section: Methods For Developing Infection-resistant Surface Modificat...mentioning

confidence: 99%

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Infection Resistant Surface Coatings by Polymer Brushes: Strategies to Construct and Applications

Dhingra

Sharma

Saha

2022

ACS Appl. Bio Mater.

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Bacteria-assisted infections on biomaterials used inside a body as an implant/device are one of the major threats to human health. Microbial-resistant coatings on biomaterials can potentially be considered to mitigate the biomaterial-associated infections. Usually biomaterials with leachable antimicrobial coatings, though economically attractive, provide only short-term protection of the surface against bacteria. Therefore, a stable, nonfouling or bactericidal, and biocompatible polymeric coating is highly desirable. In this regard, polymer brushes, defined as polymer chains tethered to a surface by one end, with suitable antiinfective functionality, represent a useful class of stable coatings which are covalently connected to the underlying surface, thus prolonging the infection resistance of the coated surface. Surface-initiated atom transfer radical polymerization (SI-ATRP) is a versatile technique for the generation of polymeric brushes via "grafting from" way. In this review, we have attempted to give a brief overview about the recent developments of surface coatings by infection-resistant polymer brushes synthesized via SI-ATRP and their applications in the biomedical field. On the basis of their charges, these anti-infective brushes can be classified into five different categories such as neutral, cationic, anionic, zwitterionic, and mixed brushes. The working mechanism of each type of brush in repelling (nonfouling/bacteriostatic) and/or killing (bactericidal) the bacteria has also been discussed. A brief summary of their future scope is also highlighted.

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Section: Methods For Developing Infection-resistant Surface Modificat...mentioning

confidence: 99%

Section: Methods For Developing Infection-resistant Surface Modificat...mentioning

confidence: 99%

Infection Resistant Surface Coatings by Polymer Brushes: Strategies to Construct and Applications

Dhingra

Sharma

Saha

2022

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…80 In the absence of substrate, resazurin and its reduction product, fluorescent resorufin, could be directly detected by LDI-MS. Based on the ability of viable microorganisms to reduce resazurin from blue to pink, Scimone et al established a method to correlate the time required for this color change with the number of viable microorganisms. 95…”

Section: Culture-based Methodsmentioning

confidence: 99%