Development of a Non-migrating Electromagnetic Transponder System for Lung Tumor Tracking

Mayse, Martin L.; Smith, R. L.; Park, M.; Monteon, G.H.; Silver, E; Parikh, Parag J.; Misselhorn, David; Talcott, Michael; Dimmer, S.; Bradley, Jeffrey D.

doi:10.1016/j.ijrobp.2008.06.1352

Cited by 13 publications

(13 citation statements)

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“…Early studies have shown that the present design of Calypso transponders (such as those used in this work) show good to moderate short-term but low long-term fixation rates (33). However, in a more recent study using an improved, ''non-migrating'' transponder design, 100% fixation rates over a 60-day period were reported for 54 bronchoscopically implanted transponders (nine per animal) (34). Interfraction transponder migration and intrafraction transponder migration are other potential concerns, particularly for implantation within the lung.…”

Section: Discussionmentioning

confidence: 73%

Toward Submillimeter Accuracy in the Management of Intrafraction Motion: The Integration of Real-Time Internal Position Monitoring and Multileaf Collimator Target Tracking

Sawant¹,

Smith

Venkat³

et al. 2009

International Journal of Radiation Oncology*Biology*Physics

101

111

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Section: Discussionmentioning

confidence: 73%

Toward Submillimeter Accuracy in the Management of Intrafraction Motion: The Integration of Real-Time Internal Position Monitoring and Multileaf Collimator Target Tracking

Sawant¹,

Smith

Venkat³

et al. 2009

International Journal of Radiation Oncology*Biology*Physics

101

111

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“…Our group has published work with a modified transponder design which shows a 100% fixation rate within the lung for 54 fiducials. 23 Other groups have published results using gold seeds which show comparable fixation rates (120=123 21 , 11=11 24 , 10=10 4 ). Internal anatomy tends to shrink as a result of radiation FIG.…”

Section: Discussionmentioning

confidence: 97%

The correlation of tissue motion within the lung: implications on fiducial based treatments

et al. 2011

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In radiation therapy many motion management and alignment techniques rely on the accuracy of an internal fiducial acting as a surrogate for target motion within the lung. Although fiducials are routinely used as surrogates for tumor motion, the extent to which varying spatial locations in the lung move similarly to other locations has yet to be quantitatively analyzed. In an attempt to analyze the motion correlation throughout the lung, ten primary lung cancer patients underwent IRB-approved 4DCT scans in the supine position. Deformable registration produced motion vectors for each voxel between exhalation and inhalation. Modeling was performed for each vector and all surrounding vectors within the lung in order to determine the mean 3D Euclidean distance necessary for an implanted fiducial to correlate with surrounding tissue motion to within 3 mm (left lower: 1.7 cm, left upper: 2.1 cm, right lower 1.6 cm, and right upper 2.9 cm). No general implantation rule of where to position a fiducial with respect to the tumor was found as the motion is highly patient and lobe specific. Correlation maps are presented showcasing spatial anisotropy of the motion of tissue surrounding the tumor.

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“…A recent study showed 100% long-term fixation rates for these transponders implanted bronchoscopically into canine lungs (26).…”

Section: Discussionmentioning

confidence: 99%

Electromagnetic Real-Time Tumor Position Monitoring and Dynamic Multileaf Collimator Tracking Using a Siemens 160 MLC: Geometric and Dosimetric Accuracy of an Integrated System

Krauß

Nill

Tacke

et al. 2011

International Journal of Radiation Oncology*Biology*Physics

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Development of a Non-migrating Electromagnetic Transponder System for Lung Tumor Tracking

Cited by 13 publications

References 0 publications

Toward Submillimeter Accuracy in the Management of Intrafraction Motion: The Integration of Real-Time Internal Position Monitoring and Multileaf Collimator Target Tracking

Toward Submillimeter Accuracy in the Management of Intrafraction Motion: The Integration of Real-Time Internal Position Monitoring and Multileaf Collimator Target Tracking

The correlation of tissue motion within the lung: implications on fiducial based treatments

Electromagnetic Real-Time Tumor Position Monitoring and Dynamic Multileaf Collimator Tracking Using a Siemens 160 MLC: Geometric and Dosimetric Accuracy of an Integrated System

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