Development of a new nanofiber scaffold for use with stem cells in a third degree burn animal model

Steffens, Daniela; Leonardi, Dilmar Francisco; Soster, Paula Rigon da Luz; Lersch, Michelle; Rosa, André Ricardo Pereira da; Crestani, Thayane Antoniolli; Scher, Cristiane Regina; Morais, Michele Greque de; Costa, Jorge Alberto Vieira; Pranke, Patrícia

doi:10.1016/j.burns.2014.03.008

Cited by 45 publications

(36 citation statements)

References 37 publications

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“…The microbial metabolism degrades and removes pollutants, which generates fewer environmentally harmful products. In this scenario, microalgae have been studied for wastewater treatment, toxic metal bioremediation, carbon dioxide (CO 2 ) biofixation and biofuel, and for biopolymer and nanofiber production …”

Section: Introductionmentioning

confidence: 99%

“…In this scenario, microalgae have been studied for wastewater treatment, toxic metal bioremediation, 1,2 carbon dioxide (CO 2 ) biofixation 3 and biofuel, 4 and for biopolymer and nanofiber production. 5,6 Various cultivation conditions have been studied to increase the microalgal biomass productivity and reduce production costs. Semi-continuous cultivations have several advantages compared with batch and continuous processes.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of different modes of operation for the production ofSpirulinasp.

Moreira

Costa

Morais

2015

J. Chem. Technol. Biotechnol.

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BACKGROUND: Semi-continuous microalgae cultivations are large-scale production alternatives that maintain high microorganism growth rates. Studies show that semi-continuous cultivation can be conducted in two ways. In one, a blend concentration is set for the linear phase. The other uses a time interval dilution. This present work aimed to determine which mode of semi-continuous cultivation of Spirulina sp. LEB 18 presented the best kinetic response.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of different modes of operation for the production ofSpirulinasp.

Moreira

Costa

Morais

2015

J. Chem. Technol. Biotechnol.

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“…Drugs-eluting nanofibers provide a sustained release of antibiotics, and analgesics and growth factors/peptides enhance the healing of burn wounds [154][155][156]. Recent studies have incorporated proteins, particularly enzymes and growth factors, into treating various medical conditions (Figure 4).…”

Section: Multibiofunctional Nanofibersmentioning

confidence: 98%

Nanofibers Used for the Delivery of Analgesics

Tseng

Liu²

2015

Nanomedicine (Lond.)

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Nanofibers are extremely advantageous for drug delivery because of their high surface area-to-volume ratios, high porosities and 3D open porous structures. Local delivery of analgesics by using nanofibers allows site-specificity and requires a lower overall drug dosage with lower adverse side effects. Different analgesics have been loaded onto various nanofibers, including those that are natural, synthetic and copolymer, for various medical applications. Analgesics can also be singly or coaxially loaded onto nanofibers to enhance clinical applications. In particular, analgesic-eluting nanofibers provide additional benefits to preventing wound adhesion and scar formation. This paper reviews current research and breakthrough discoveries on the innovative application of analgesic-loaded nanofibers that will alter the clinical therapy of pain.

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“…Apart from the biomimetic properties and being ecologically safe, they are available from plenty of replenishable agricultural food resources and various biodegradable waste materials which reduce their synthesis and processing cost. Natural biomaterials show good biocompatibility and biodegradability [16] with possibility of producing various enzymatically modified derivatives that stimulates cell growth and attachment with minimal risk of tissue rejection [17,18]. Biomaterials derived from natural sources include polysaccharides, proteins, bioceramics, etc.…”

Section: Introductionmentioning

confidence: 99%

Naturally derived biomaterials for development of composite bone scaffold: A review

Barua

Deoghare

Deb

et al. 2018

IOP Conf. Ser.: Mater. Sci. Eng.

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E-mail: imon18enator@gmail.comAbstract. Over the last few decades, there has been an increasing demand of tissue engineered bone scaffolds as a substitute material for diseased or damaged bone segments. A variety of synthetic and natural biomaterials have been explored by researchers for development of composite scaffold. Naturally derived biomaterials have the advantages of immunomodulating, anti-toxic and biomimetic properties with the cellular environment in vivo, when compared to synthetic biomaterials. In this paper, different protein and polysaccharide based biomaterials used for developing composite bone scaffolds are reviewed. The properties of composite scaffolds developed from these biomaterials are highlighted. The study also includes different natural materials and biowastes which are used for deriving bioceramics for producing composite bone scaffolds. The overall study gives a brief idea on the importance of protein and polysaccharide based biomaterials and bioceramics for composite bone scaffold development and scope for future work in the field of naturally derived biomaterials.

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Development of a new nanofiber scaffold for use with stem cells in a third degree burn animal model

Cited by 45 publications

References 37 publications

Evaluation of different modes of operation for the production ofSpirulinasp.

Evaluation of different modes of operation for the production ofSpirulinasp.

Nanofibers Used for the Delivery of Analgesics

Naturally derived biomaterials for development of composite bone scaffold: A review

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