Development of a New Inflow Valve for a 20cc Semisoft Ventricle: Preliminary Results

Eg, Wijsmuller; Ls, Yu; Yuan, B; Nd, Bishop; Wj, Kolff

doi:10.1177/039139889001300810

Cited by 7 publications

(4 citation statements)

References 1 publication

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“…From a structural and mechanical properties point of view, it has been hypothesized that valve leaflet material fabricated from fibrereinforced composite material that mimics the native valve leaflet structure and properties will optimize leaflet stresses and decrease tears and perforations [1]. Materials that have been considered over the past years including poly(tethrafluroethylene), poly (vinyl chloride), segmented poly(urethane), silicon rubber, and poly(ether urethane urea) all have shortcomings in fatigue life and calcification complications [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Design and simulation of a poly(vinyl alcohol)—bacterial cellulose nanocomposite mechanical aortic heart valve prosthesis

Mohammadi

Boughner

Millon

et al. 2009

Proc Inst Mech Eng H

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In this study, a polymeric aortic heart valve made of poly(vinyl alcohol) (PVA)-bacterial cellulose (BC) nanocomposite is simulated and designed using a hyperelastic non-linear anisotropic material model. A novel nanocomposite biomaterial combination of 15 wt % PVA and 0.5 wt % BC is developed in this study. The mechanical properties of the synthesized PVA-BC are similar to those of the porcine heart valve in both the principal directions. To design the geometry of the leaflets an advance surfacing technique is employed. A Galerkin-based non-linear finite element method is applied to analyse the mechanical behaviour of the leaflet in the closing and opening phases under physiological conditions. The model used in this study can be implemented in mechanical models for any soft tissues such as articular cartilage, tendon, and ligament.

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Section: Introductionmentioning

confidence: 99%

Design and simulation of a poly(vinyl alcohol)—bacterial cellulose nanocomposite mechanical aortic heart valve prosthesis

Mohammadi

Boughner

Millon

et al. 2009

Proc Inst Mech Eng H

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“…Material models implemented in previous works for modeling heart valve leaflet tissue mechanics can be generally grouped into four categories: elastic and isotropic [122][123][124][125][126], hyperelastic and isotropic [127][128][129][130], elastic and anisotropic [131][132][133] and hyperelastic and anisotropic [134,135]. There have been models developed to study the role of geometry and a non-uniform leaflet thickness on stress distribution in a porcine valve tissue [136,137].…”

Section: Modeling Of Aortic Heart Valve Leafletmentioning

confidence: 99%

Prosthetic aortic heart valves: Modeling and design

Mohammadi

Mequanint

2011

Medical Engineering & Physics

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“…All these materials are associated with some short-and long-term complications. [3][4][5][6] In this study, we offer low-temperature freezing and thawing cycled polyvinyl alcohol (PVA) cryogel reinforced by bacterial cellulose (BC) natural nanofibers with excellent biocompatible properties. A novel onepiece PVA-BC cryogel trileaflet heart valve in a Nitinol basket is designed, optimized and fabricated.…”

Section: Introductionmentioning

confidence: 99%

Proposed percutaneous aortic valve prosthesis made of cryogel

Mohammadi

Goode

Fradet

et al. 2019

Proc Inst Mech Eng H

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Transcatheter heart valves are promising for high-risk patients. Generally, their leaflets are made of pericardium stented in a Nitinol basket. Despite their relative success, they are associated with significant complications such as valve migration, implantation risks, stroke, coronary obstruction, myocardial infraction, acute kidney injury (which all are due to the release of detached solid calcific pieces in to the blood stream) and expected issues existing with tissue valves such as leaflet calcification. This study is an attempt to fabricate the first ever polymeric percutaneous valves made of cryogel following the geometry and mechanical properties of porcine aortic valve to address some of the above-mentioned shortcomings. A novel, one-piece, tricuspid percutaneous valve, consisting of leaflets made entirely from the hydrogel, polyvinyl alcohol cryogel reinforced by bacterial cellulose natural nanocomposite, attached to a Nitinol basket was developed and demonstrated. Following the natural geometry of the valve, a novel approach was applied based on the revolution about an axis of a hyperboloid shape. The geometry was modified based on avoiding sharp warpage of leaflets and removal of the central opening orifice area of the valve when valve is fully closed using the finite element analysis. The modified geometry was replaced by a cloud of (control) points and was essentially converted to Bezier surfaces for further adjustment. A cavity mold was then designed and fabricated to form the valve. The fabricated valve was sewn into the Nitinol basket which is covered by Dacron cloth. The models presented in this study merit further development and revisions for both aortic and mitral positions.

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Development of a New Inflow Valve for a 20cc Semisoft Ventricle: Preliminary Results

Cited by 7 publications

References 1 publication

Design and simulation of a poly(vinyl alcohol)—bacterial cellulose nanocomposite mechanical aortic heart valve prosthesis

Design and simulation of a poly(vinyl alcohol)—bacterial cellulose nanocomposite mechanical aortic heart valve prosthesis

Prosthetic aortic heart valves: Modeling and design

Proposed percutaneous aortic valve prosthesis made of cryogel

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