Development of a mutton powder certified reference material for the analysis of ractopamine

Jian, Zhou; Wang, Min; Zhang, Liyuan; Yang, Mujie; Deng, Ligang; Li, Xia; Sun, Qifan

doi:10.1016/j.jfca.2022.104935

Cited by 5 publications

(4 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Matrix CRMs are usually selected to be similar to the test sample in real state, and the value was accurately characterized [25]. Therefore, in recent years, plenty of matrix certified reference materials have been developed, such as ractopamine or salbutamol in mutton powder [26,27], enrofloxacin in whole liquid egg [28], and docosahexaenoic acid in milk powder [29], as well as florfenicol in shrimp [30] for food quality and safety monitoring.…”

Section: Introductionmentioning

confidence: 99%

Certification of a novel matrix reference material for accurate measurements of aflatoxin M1 in milk powder

Huang,

Liu,

Zhou

et al. 2024

Accred Qual Assur

Self Cite

View full text Add to dashboard Cite

In this study, two different concentrations of matrix certified reference materials (CRMs) were produced for the accurate measurement of aflatoxin M1(AFM1) in milk powder((GBW(E) 100552, GBW(E) 100553)). The raw material was obtained by feeding cows with positive drugs. The homogeneity, stability and characterization of this matrix CRMs were examined by liquid chromatography tandem mass spectrometry with isotope-labeled internal standard method. The certified value for the low concentration of AFM1 in milk powder was 2.45 µg/kg with an uncertainty of 0.43 µg/kg (coverage factor k=2, at 95% confidence). The certified value for the high concentration of AFM1 in milk powder was 3.45 µg/kg with an expanded uncertainty of 0.49 µg/kg (coverage factor k=2, at 95% confidence). In addition, the samples were evaluated in detail for homogeneity, long-term stability at -80°C for 6 months, and short-term stability at 4°C for 7 days. The results showed that the samples were stable under the above conditions.

show abstract

Section: Introductionmentioning

confidence: 99%

Certification of a novel matrix reference material for accurate measurements of aflatoxin M1 in milk powder

Huang,

Liu,

Zhou

et al. 2024

Accred Qual Assur

Self Cite

View full text Add to dashboard Cite

show abstract

“…Currently, analytical methods for detecting Rac in pork are limited to techniques requiring highly sophisticated sample preparation or costly instrumentation, such as enzyme-linked immunosorbent assay (ELISA), high-performance liquid chromatography (HPLC), gas chromatography–mass spectrometry (GC–MS), and liquid chromatography–tandem mass spectrometry (LC–MS/MS). − ELISA offers a rapid and portable method for detecting Rac; however, its major drawback is its requirements of complicated time-consuming sample pretreatment and preparation because of the complex matrix of animal tissues . Among instrumental techniques, HPLC enables multicomponent and highly sensitive analysis; however, the HPLC instrument is costly and nonportable, which prevents its widespread application .…”

Section: Introductionmentioning

confidence: 99%

Nafion/Silver Nanoparticles as an Electrochemically Sensitive Interface for the Detection of Ractopamine in Pork Liver

Chi,

Hsiao,

et al. 2023

ACS Omega

View full text Add to dashboard Cite

“…The purity evaluation of a pure organic compound using valid methods is essential to be metrologically traceable to the International System of Units (SI) for chemical measurements. Pure organic substances, as primary standard materials, are crucial in characterizing certified reference materials (CRM) [1][2][3]. The mass balance approach (MBA) has been widely applied to determine the mass fraction of the main components of pure organic material [4][5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

“…The purity of materials without chromophores, such as monosaccharides, was evaluated using high-performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) [9]. As described in previous studies, the purity values assigned by MBA can be applied to correct the concentration of the standard solution for the quantification [2,3]. Comprehensive analytical methods for purity evaluation were employed in these studies to obtain reliable and SI-traceable values for salt compounds.…”

Section: Introductionmentioning

confidence: 99%

Analytical Methods Based on the Mass Balance Approach for Purity Evaluation of Tetracycline Hydrochloride

Lee,

Baek,

Kwon

et al. 2023

Molecules

View full text Add to dashboard Cite

Analytical methods based on the mass balance approach were developed for the purity evaluation of tetracycline hydrochloride, a representative salt compound used in pure veterinary drug analysis. The purity assignment method was used to quantify individual classes of impurities via independent analytical techniques. The mass fraction of the free base or salt form contained in a high-purity organic compound with a hydrochloride salt can be determined. The chloride content by ion chromatography-conductivity detector (IC-CD) and general classes of impurities, including structurally related impurities by liquid chromatography–ultraviolet (LC-UV) detector, water by Karl Fischer (KF) coulometric titration, residual solvents by headspace sampler gas chromatography/mass spectrometry (HS-GC/MS), and non-volatiles by thermogravimetric analyzer (TGA), were considered to calculate the purity of the mass fraction. The chloride content of the salt compound can be considered the main impurity in the mass fraction of the free base in the salt compound. A purity assay using quantitative nuclear magnetic resonance (q-NMR) as a direct determination method was performed to confirm the results of the mass balance method. The assigned purities of the tetracycline free form and its salt form in mass fraction were (898.80 ± 1.60) mg/g and (972.65 ± 1.58) mg/g, respectively, which are traceable to the international system of units (SI). Thus, the procedure for evaluating the purity of the free base and salt forms in the salt compound is newly demonstrated in this study.

show abstract

Development of a mutton powder certified reference material for the analysis of ractopamine

Cited by 5 publications

References 21 publications

Certification of a novel matrix reference material for accurate measurements of aflatoxin M1 in milk powder

Certification of a novel matrix reference material for accurate measurements of aflatoxin M1 in milk powder

Nafion/Silver Nanoparticles as an Electrochemically Sensitive Interface for the Detection of Ractopamine in Pork Liver

Analytical Methods Based on the Mass Balance Approach for Purity Evaluation of Tetracycline Hydrochloride

Contact Info

Product

Resources

About