Development of a multivariate model to predict the likelihood of carcinoma in patients with indeterminate peripheral lung nodules after a nondiagnostic bronchoscopic evaluation

Multitarget fluorescence in situ hybridization assay for the detection of lung cancer in bronchial cytology specimens

“…Currently, the suspicion index should be increased, and the patients should be followed up closely clinically. Recently, Voss et al have proposed a clinical prediction model using multivariate, including clinical features, radiologic features and non‐positive bronchial cytology/FISH testing algorithm, to further stratify patient's risk of being diagnosed with lung cancer after initial nondiagnostic bronchial cytology . After multivariate analysis, hypertetrasomy FISH, pack years, age, atypical or suspicious cytology, and nodule spiculation have been found to be independent risk predictors.…”