Development of a multi-task formaldehyde specific fluorescent probe for bioimaging in living systems and decoration materials analysis

Li, Jiangfeng; Ding, Donghao; Wang, Jiangyan; Xu, Lizhen; Tan, Dan; Lin, Weiying

doi:10.1016/j.cej.2022.137634

Cited by 9 publications

(2 citation statements)

References 24 publications

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“…36,37 In particular, FA-responsive uorescent probes that are selectively localized to different organelles such as the nucleus, endoplasmic reticulum (ER), mitochondria, and lysosomes have also been developed. [38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53] These probes are however largely based on the formimine-or aminal-formation activity of FA (Table S1 in ESI †). The 2-aza-Cope reactivity has been less oen utilized to construct organelle-targeting FA probes.…”

Section: Introductionmentioning

confidence: 99%

Modular development of organelle-targeting fluorescent probes for imaging formaldehyde in live cells

Zhang,

Du,

Liao

et al. 2024

Anal. Methods

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Section: Introductionmentioning

confidence: 99%

Modular development of organelle-targeting fluorescent probes for imaging formaldehyde in live cells

Zhang,

Du,

Liao

et al. 2024

Anal. Methods

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“…Nevertheless, these methods are not applicable to H 2 S detection at the cellular level or in vivo. Fluorescence techniques are increasingly popular because of excellent sensitivity and specificity, short detection time, low cost, simple operation, and high spatial and temporal resolution [16][17][18][19]. Therefore, fluorescence technology to detect H 2 S is undoubtedly an excellent method.…”

Section: Introductionmentioning

confidence: 99%

Development of a New Hydrogen Sulfide Fluorescent Probe Based on Coumarin–Chalcone Fluorescence Platform and Its Imaging Application

Chi

Zhang

et al. 2023

Chemosensors

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Hydrogen sulfide (H2S), as one of the critical gaseous signaling molecules, has important physiological functions in the human body, and abnormal levels of hydrogen sulfide are closely related to tumors, Parkinson’s disease, Alzheimer’s disease, and other diseases. In order to enable the detection of H2S in the physiological environment, herein, a new H2S fluorescence probe, named C-HS, based on a coumarin–chalcone fluorescence platform was developed. The fluorescence probe provides specific recognition of H2S within a wide pH detection range (5.5–8.5), a rapid recognition response (within 10 min) for H2S molecules, and a high selectivity for competing species. The probe C-HS possesses low cytotoxicity and is used to achieve the detection of exogenous/ endogenous H2S in living cells, indicating that the constructed probe C-HS has the ability to track changes in intracellular H2S levels. Therefore, probe C-HS could be a potential tool for the early diagnosis of H2S-related diseases.

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Synthesis of an Amine Moiety‐Based Fluorescent Probe and the Relationship Between the Amino Substitution Position and Formaldehyde Detection Performance

Tan,

Hua,

Wang

et al. 2024

ChemistrySelect

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A novel amine moiety‐based fluorescent probe (BA) was prepared using diphenylacetylene as fluorophore and amino group as acceptor. The probe achieves detection of formaldehyde through fluorescence enhancement by inhibition the photoinduced electron transfer (PET) between diphenylacetylene and amino group. And the different formaldehyde detection performance of 2‐(phenylethynyl)aniline (BA‐1), 3‐(phenylethynyl)aniline (BA‐2) and 4‐(phenylethynyl)aniline (BA‐3) indicates that the position of amino recognition group on the benzene ring of diphenylacetylene has a significant impact on the detection ability of this type fluorescent probe. When the amino group is in the ortho‐position of the benzene ring, probe BA‐1 can rapidly enhance the fluorescence intensity within 20 min with limit of detection as low as 0.75 μM; When the amino group is located in meta‐position of benzene ring, the solution of BA‐2 also exhibited a certain degree of fluorescence enhancement, but it is weaker than BA‐1; When the amino group is at the para‐position of benzene ring, BA‐3 has almost no response to formaldehyde.

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Development of a multi-task formaldehyde specific fluorescent probe for bioimaging in living systems and decoration materials analysis

Cited by 9 publications

References 24 publications

Modular development of organelle-targeting fluorescent probes for imaging formaldehyde in live cells

Modular development of organelle-targeting fluorescent probes for imaging formaldehyde in live cells

Development of a New Hydrogen Sulfide Fluorescent Probe Based on Coumarin–Chalcone Fluorescence Platform and Its Imaging Application

Synthesis of an Amine Moiety‐Based Fluorescent Probe and the Relationship Between the Amino Substitution Position and Formaldehyde Detection Performance

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