Development of a Multi-Energy CT for Small Animals: Characterization of the Quasi-Monochromatic X-Ray Source

Masetti, Simone; Fiaschetti, M.; Turco, Anna; Roma, L.; Rossi, Pier Luca; Mariselli, M.; Lanconelli, Nico; Baldazzi, G.

doi:10.1109/tns.2008.2008184

Cited by 11 publications

(4 citation statements)

References 11 publications

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“…These detectors are capable of counting discrete photon interactions, and multiple monoenergetic images can be obtained with single image acquisition. Several studies have been conducted with multi-energy CT[ 12 13 14 ] and include K-edge imaging using contrast agents. [ 9 15 ] These contrast images can be used for tissue differentiation or quantification and proved to be useful in multiple studies.…”

Section: Introductionmentioning

confidence: 99%

Multi-energy computed tomography breast imaging with Monte Carlo simulations: Contrast-to-noise-based image weighting

Eeden

Plessis

2019

J Med Phys

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Section: Introductionmentioning

confidence: 99%

Multi-energy computed tomography breast imaging with Monte Carlo simulations: Contrast-to-noise-based image weighting

Eeden

Plessis

2019

J Med Phys

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“…The use of monochromatic radiation can eliminate cupping artifacts and accomplish a one-to-one relationship between grey values and materials [ 6 ]. But it is impractical to apply monochromatic radiation in the typical CT system [ 7 , 8 ]. One feasible method is to synthesize monochromatic images using dual-energy imaging.…”

Section: Introductionmentioning

confidence: 99%

“…It can be accomplished through multienergy imaging, which may require an X-ray photon counting detector [ 11 , 12 ]. Multienergy imaging can be seen an extension of dual-energy CT [ 7 , 13 ]. The photon counting detector can count discrete photon interactions [ 14 ] and has energy selectivity.…”

Section: Introductionmentioning

confidence: 99%

Narrow-Energy-Width CT Based on Multivoltage X-Ray Image Decomposition

Wei

Han

Chen

2017

International Journal of Biomedical Imaging

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A polychromatic X-ray beam causes the grey of the reconstructed image to depend on its position within a solid and the material being imaged. This factor makes quantitative measurements via computed tomography (CT) imaging very difficult. To obtain a narrow-energy-width reconstructed image, we propose a model to decompose multivoltage X-ray images into many narrow-energy-width X-ray images by utilizing the low frequency characteristics of X-ray scattering. It needs no change of hardware in the typical CT system. Solving the decomposition model, narrow-energy-width projections are obtained and it is used to reconstruct the image. A cylinder composed of aluminum and silicon is used in a verification experiment. Some of the reconstructed images could be regarded as real narrow-energy-width reconstructed images, which demonstrates the effectiveness of the proposed method.

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“…Several studies have shown the potential of reducing the dose in different medical applications, while maintaining the same image quality [1,2]. However, it is very challenging to get a monochromatic source with a sufficient flux for small animal or human CT. Our group has gained some experience in the last years in the development of quasi-monochromatic X-ray beams with application in medicine [3,4]. These sources were obtained by the Bragg diffraction of photons coming from conventional X-ray tubes, and can provide fluxes sufficient for CT inspections.…”

Section: Introductionmentioning

confidence: 99%

Preliminary results of a Multi-Energy CT system for small animals

et al. 2009

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The system makes use of a set of quasi-monochromatic X-ray beams, with energy tunable in a range from 26 to 72 keV. These beams are produced by Bragg diffraction on a Highly Oriented Pyrolytic Graphite crystal. With quasi-monochromatic sources it is possible to perform multi-energy investigation in a more effective way, as compared with conventional X-ray tubes. Triple-energy projection allows to combine a set of three quasimonochromatic images of an object, in order to obtain a corresponding set of three single-tissue images, which are the mass-thickness map (product of density and thickness) of three reference materials. The triple-energy technique can be applied to the mass-thickness-map reconstruction of a contrast medium, because it is able to remove completely the signal due to other tissues (i.e. the structural background noise). Here, we present a description of the system and the methods for combining the images at the different energies. We also show some results of images acquired at three different energies and of the reconstructed information about the contrast medium (Iodine). We achieved that the measurement of the Iodine mass-thickness agrees very well with the known concentration of the injected Iodine solution.

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Development of a Multi-Energy CT for Small Animals: Characterization of the Quasi-Monochromatic X-Ray Source

Cited by 11 publications

References 11 publications

Multi-energy computed tomography breast imaging with Monte Carlo simulations: Contrast-to-noise-based image weighting

Multi-energy computed tomography breast imaging with Monte Carlo simulations: Contrast-to-noise-based image weighting

Narrow-Energy-Width CT Based on Multivoltage X-Ray Image Decomposition

Preliminary results of a Multi-Energy CT system for small animals

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