Development of a microarray lateral flow strip test using a luminescent organic compound for multiplex detection of five mycotoxins

Charlermroj, Ratthaphol; Phuengwas, Sudtida; Makornwattana, Manlika; Sooksimuang, Thanasat; Sahasithiwat, Somboon; Panchan, Waraporn; Sukbangnop, Wannee; Elliott, Christopher T.; Karoonuthaisiri, Nitsara

doi:10.1016/j.talanta.2021.122540

Cited by 41 publications

(19 citation statements)

References 58 publications

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“…Following good agricultural and good manufacturing practices is the cornerstone to pursue this goal [ 48 ]. However, only a widespread network of controls can further minimize the risk [ 2 , 47 , 49 ].…”

Section: Applicationsmentioning

confidence: 99%

“…A possible solution might be the use of the microarray format that owns the right peculiarities to improve the multiplex capability. Although very promising, this approach has been reported just a few times in the literature [ 2 , 287 , 288 , 289 , 290 ] and the reason of this under-use may be mainly associated to the possible microfluidic modification in using a microarray pattern on the membrane instead of the lines pattern, and to the more complex readability of the results that may cause misleading results interpretation. A deeper and more accurate study of the microarray LFIA and the use of a reading device could help its spread in the near future.…”

Section: Future Perspectivesmentioning

confidence: 99%

“…Conventional laboratory-based analytical methods like high-performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), enzyme-linked immunosorbent assay (ELISA) and real time polymerase chain reaction (qPCR) usually require complex and long procedures to obtain a result [ 1 , 2 , 3 ], but several situations often require a fast and on-site analyte detection [ 4 , 5 ]. As a consequence, in the last decades, the scientific research has been focused more and more on the development and optimization of portable, affordable, and user-friendly rapid methods of analysis for point-of-need (PON) testing [ 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

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Ten Years of Lateral Flow Immunoassay Technique Applications: Trends, Challenges and Future Perspectives

Nardo

Chiarello

Cavalera

et al. 2021

Sensors

236

162

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The Lateral Flow Immunoassay (LFIA) is by far one of the most successful analytical platforms to perform the on-site detection of target substances. LFIA can be considered as a sort of lab-in-a-hand and, together with other point-of-need tests, has represented a paradigm shift from sample-to-lab to lab-to-sample aiming to improve decision making and turnaround time. The features of LFIAs made them a very attractive tool in clinical diagnostic where they can improve patient care by enabling more prompt diagnosis and treatment decisions. The rapidity, simplicity, relative cost-effectiveness, and the possibility to be used by nonskilled personnel contributed to the wide acceptance of LFIAs. As a consequence, from the detection of molecules, organisms, and (bio)markers for clinical purposes, the LFIA application has been rapidly extended to other fields, including food and feed safety, veterinary medicine, environmental control, and many others. This review aims to provide readers with a 10-years overview of applications, outlining the trends for the main application fields and the relative compounded annual growth rates. Moreover, future perspectives and challenges are discussed.

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Section: Applicationsmentioning

confidence: 99%

Section: Future Perspectivesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Ten Years of Lateral Flow Immunoassay Technique Applications: Trends, Challenges and Future Perspectives

Nardo

Chiarello

Cavalera

et al. 2021

Sensors

236

162

View full text Add to dashboard Cite

show abstract

“…Indeed, the number of individual dots that can be spotted in a strip is much larger than the number of T lines. As an example, Charlermroj introduced an ICA strip with ordered rows of spots containing five mycotoxins antigens (Charlermroj et al., 2021). Correspondently, five signal probes (fluorescent M424 dye‐labeled antibodies) were simultaneously captured by such a multiarray strip.…”

Section: Strategies and Applications Of Mobas In Food Safety Analysismentioning

confidence: 99%

Multiplex optical bioassays for food safety analysis: Toward on‐site detection

Guan

Jin

et al. 2022

Comp Rev Food Sci Food Safe

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Food safety analysis plays a significant role in controlling food contamination and supervision. In recent years, multiplex optical bioassays (MOBAs) have been widely applied to analyze multiple hazards due to their efficiency and low cost. However, due to the challenges such as multiplexing capacity, poor sensitivity, and bulky instrumentation, the further application of traditional MOBAs in food screening has been limited. In this review, effective strategies regarding food safety MOBAs are summarized, such as spatial‐resolution modes performed in multi‐T lines/dots strips or arrays of strip/microplate/microfluidic chip/SPR chip and signal‐resolution modes employing distinguishable colorimetric/luminescence/fluorescence/surface plasma resonance/surface‐enhanced Raman spectrum as signal tags. Following this, new trends on how to design engineered sensor architecture and exploit distinguishable signal reporters, how to improve both multiplexing capacity and sensitivity, and how to integrate these formats into smartphones so as to be mobile are summarized systematically. Typically, in the case of enhancing multiplexing capacity and detection throughput, microfluidic array chips with multichannel architecture would be a favorable approach to overcome the spatial and physical limitations of immunochromatographic assay (ICA) test strips. Moreover, noble metal nanoparticles and single‐excitation, multiple‐emission luminescence nanomaterials hold great potential in developing ultrasensitive MOBAs. Finally, the exploitation of innovative multiplexing strategy hybridized with powerful and widely available smartphones opens new perspectives to MOBAs. In future, the MOBAs should be more sensitive, have higher multiplexing capacity, and easier instrumentation.

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“…Recently a 'hybrid' format incorporating LFIA and microarrays was explored for the assay of five mycotoxins (Charlermroj et al, 2021). The format involved spotting a 7×4 array, rather than the traditional lines, onto the signal pad of the LFIA device.…”

Section: Multiplexed Sensor Arraysmentioning

confidence: 99%

Developments in mycotoxin analysis: an update for 2020-2021

Tittlemier¹,

Cramer

Dall’Asta

et al. 2022

WMJ

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This review summarises developments published in the period from mid-2020 to mid-2021 on the analysis of a number of diverse matrices for mycotoxins. Notable developments in all aspects of mycotoxin analysis, from sampling and quality assurance/quality control of analytical results, to the various detection and quantitation technologies ranging from single mycotoxin biosensors to comprehensive instrumental methods are presented and discussed. The summary and discussion of this past year’s developments in detection and quantitation technology covers chromatography with targeted or non-targeted high resolution mass spectrometry, tandem mass spectrometry, detection other than mass spectrometry, biosensors, as well as assays using alternatives to antibodies. This critical review aims to briefly present the most important recent developments and trends in mycotoxin determination, as well as to address limitations of the presented methodologies.

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Development of a microarray lateral flow strip test using a luminescent organic compound for multiplex detection of five mycotoxins

Cited by 41 publications

References 58 publications

Ten Years of Lateral Flow Immunoassay Technique Applications: Trends, Challenges and Future Perspectives

Ten Years of Lateral Flow Immunoassay Technique Applications: Trends, Challenges and Future Perspectives

Multiplex optical bioassays for food safety analysis: Toward on‐site detection

Developments in mycotoxin analysis: an update for 2020-2021

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