Development of a method to evaluate the effects of external environments on drug stability in nails using micro‐segmental analysis
Kenji Kuwayama,
Hajime Miyaguchi,
Tatsuyuki Kanamori
et al.
Abstract:Nails can be used as an alternative to hair for examining past drug use. However, daily hand‐and‐nail care can eliminate the internal drugs. Therefore, we developed an evaluation method to examine the effects of the external environment on drug stability in nails using micro‐segmental analysis. First, reference nails containing drugs were prepared by collecting fingernails from participants who had consumed hay‐fever medicines continuously for 4 months. Next, the entire free edge of a reference nail was cut in… Show more
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