Development of a Method for the Simultaneous Determination of Six Sulfonylurea Herbicides in Wheat, Rice, and Corn by Liquid Chromatography–Tandem Mass Spectrometry

Abstract

A sensitive and reliable method was developed and validated for trace determination of sulfonylurea herbicides residues in cereals (wheat, rice, and corn) by liquid chromatography-tandem mass spectrometry. The selected analytes were ethoxysulfuron, ethametsulfuron-methyl, bensulfuron-methyl, chlorimuron-ethyl, pyrazosulfuron-ethyl, and cyclosulfamuron. In this work, the extraction procedure was performed by using a mixture solvent of phosphate buffer (pH 9.5)/acetonitrile (8:2, v/v) as the extraction solvent and then was cleaned up by using Spe-ed C18/18% SPE cartridges, providing good recoveries for all of the tested analytes and with no matrix effects affecting method accuracy. The limits of detection for the studied analytes in cereal samples were between 0.043 and 0.23 μg kg(-1), and the limits of quantification were between 0.14 and 0.77 μg kg(-1), lower in all cases than the maximum residue limits permitted by the European Union for this kind of food. The developed methodology has demonstrated its suitability for the monitoring of these residues in cereal samples with high sensitivity, precision, and satisfactory recoveries.

Field bindweed (Convolvulus arvensis L.) and redroot pigweed (Amaranthus retroflexus L.) control in potato by pre- or post-emergence applied flumioxazin and sulfosulfuron

“…The analysis detection limit was 0.01 mg kg -1 . Regarding the determination of sulfosulforon, the potato samples were prepared according to Kang's method with slight modifications (Kang et al, 2011). In particular, 500 g of each sample was chopped in small pieces and homogenized.…”

Application of Solvent Demulsification-Dispersive Liquid-Liquid Microextraction Based on Solidification of Floating Organic Drop Coupled with High Perfomence Liquid Chromatography in Determination of Sulfonylurea Herbicides in Water and Soil

“…They are soluble in basic solutions. According to the references, 8,9 0.1 mol L -1 of NaHCO 3 containing 2% methanol was selected as the extraction solvent of soil samples in the experiment and the recoveries of 75-110% were obtained.…”

“…Due to the fact that sulfonylurea herbicides residues in environment might be harmful to some animals and plants, it is necessary to develop a reliable analytical method for the detection of sulfonylurea herbicides residues in environment. Several analytical methods have been developed to determine sulfonylurea herbicide residues, including high performance liquid chromatography with ultraviolet detection (HPLC-UV), [4][5][6] gas chromatography (GC), 7 high performance liquid chromatography coupled to mass spectrometry (HPLC-MS), 8 gas chromatography coupled to mass spectrometry (GC-MS) 9 and so on. 10 Since most of sulfonylurea herbicides were instable at high temperature, a time consuming procedure of sample derivatization or hydrolyzation was required prior to analysis with GC and GC-MS, which limited the application of GC and GC-MS in determination of sulfonylureas.…”

Artificial neural network-based equation to predict the toxicity of herbicides on rats

“…They are also found in agricultural and animal products (wheat, corn, fruits, vegetables, cereals, tea, fish, milk, eggs, meat, honey and medicinal herbs, etc.) [11][12][13][14]. As a result, this contamination could give rise to serious health and safety problems for consumers.…”