“…26,28,32 Also for most of the DDAH1 inhibitors (both arginine and non-arginine-like) limited information of their pharmacokinetic profiles are available with only a few studies performed in animal models. Pharmacokinetic data is available for L-257 ( 13 ), ZST316 ( 20 ) and ZST152 ( 24 ) 40,41 and animal studies detailing the effects of DDAH1 inhibition of L-257 (ref. 34) and DD1E5.…”