Development of a high-precision color gamma-ray image sensor based on TSV-MPPC and diced scintillator arrays

Oshima, T.; Kataoka, J.; Kishimoto, A.; Fujita, Takuya; Kurei, Y.; Nishiyama, T.; Morita, Hayato; Yamamoto, Seiichi; Ogawa, Kōichi

doi:10.1016/j.nima.2015.08.068

Cited by 14 publications

(9 citation statements)

References 11 publications

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“…For a position-sensitive b-ray detector, we used a 35 9 35 9 1-mm 3 Ce-Doped (La, Gd) 2 Si 2 O 7 (La-GPS) scintillator, 9 which has 300-µm fine-pitch (i.e., 300-µm micro-grooved pixels) fabricated by a dicing saw. [10][11][12] We coupled the La-GPS detector to a 2-inch multianode position-sensitive photomultiplier tube (PS-PMT, Hamamatsu H8500). For the detector window, we used three sheets of 12-µm-thick aluminized Mylar foil as light shielding.…”

Section: A System Descriptionmentioning

confidence: 99%

Beta‐ray imaging system with γ‐ray coincidence for multiple‐tracer imaging

Fukuchi

Yamamoto²,

Kataoka

et al. 2019

Medical Physics

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Purpose Beta‐ray imaging systems are widely used for various biological objects to obtain a two‐dimensional (2D) distribution of β‐ray emitting radioisotopes. However, a conventional β‐ray imaging system is unsuitable for multiple‐tracer imaging, because the continuous energy distribution of β‐rays complicates distinguishing among different tracers by energy information. Therefore, we developed a new type of β‐ray imaging system, which is useful for multiple tracers by detecting coincidence γ‐rays with β‐rays, and evaluated its imaging performance. Methods Our system is composed of position‐sensitive β‐ray and γ‐ray detectors. The former is a 35 × 35 × 1‐mm3 Ce‐Doped((La, Gd)2Si2O7) (La‐GPS) scintillation detector, which has a 300‐µm pitch of pixels. The latter is a 43 × 43 × 16‐mm3 bismuth germanium oxide (BGO) scintillation detector. Both detectors are mounted on a flexible frame and placed in a user‐selectable position. We experimentally evaluated the performance of the β‐ray detector and the γ‐ray efficiencies of the γ‐ray detector with different energies, positions, and distances. We also conducted point sources and phantom measurements with dual isotopes to evaluate the system performance of multiple‐tracer imaging. Results For the β‐ray detector, the β‐ray detection efficiencies for 45Ca (245‐keV maximum energy) and 90Sr/90Y (545 and 2280‐keV maximum energy) were 14.3% and 21.9%, respectively. The total γ‐ray detection efficiency of the γ‐ray detector for all γ‐rays from 22Na (511‐keV annihilation γ‐rays and a 1275‐keV γ‐ray) in the center position with a detector distance of 20 mm was 17.5%. From a point‐source measurement using 22Na and 90Sr/90Y, we successfully extracted the position of a positron‐γ emitter 22Na. Furthermore, for a phantom experiment using 45Ca and 18F or 18F and 22Na, we successfully extracted the distribution of the second tracer using the annihilation γ‐ray or de‐excitation γ‐ray coincidence. In all the imaging experiments, the event counts of the extracted images were consistent with the counts estimated by the measured γ‐ray efficiencies. Conclusions We successfully demonstrated the feasibility of our β‐ray autoradiography system for imaging multiple isotopes. Since our system can identify not only a β‐γ emitter but also a positron emitter using the coincidence detection of annihilation γ‐rays, it is useful for PET tracers and various new applications that are otherwise impractical.

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Section: A System Descriptionmentioning

confidence: 99%

Beta‐ray imaging system with γ‐ray coincidence for multiple‐tracer imaging

Fukuchi

Yamamoto²,

Kataoka

et al. 2019

Medical Physics

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“…-high density (6.63 g/cm 3 [1]); -high light yield ((40-60) • 10 3 photon/MeV [8,9]); -radiation hardness and not hygroscopic [6,8,9]; -their emission peak release (λ em ≈ 520÷530 nm) is very close to the sensitivity peak of Si photomultiplier at λ ≈ 500 nm [4]; -transparent for their self-radiation (λ em ≈ 520÷530 nm).…”

Section: Introductionmentioning

confidence: 99%

“…Despite the above good properties the material has a disadvantage, i.e., long decay time the fast component of which is 88 ns [9]. The poor scintillation kinetics of GAGG : Ce hinder its applications.…”

Section: Introductionmentioning

confidence: 99%

Effect of Ca 2+ and Zr 4+ co-doping on the optical properties of Gd 3Al 2Ga 3O 12: Ce single crystals

Kasimova¹,

Козлова²,

Бузанов³

et al. 2019

MoEM

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Scintillation materials capable of transforming absorbed high-energy particles into visible radiation photons find multiple applications including advanced medical visualization methods. Gd3Al2Ga3O12 : Ce is a promising oxygen-containing sсintillator for fabrication of detecting crystals of positron emission tomographs due to its unique properties, e.g. high density, high light yield, radiation hardness etc. However its kinetic parameters currently restrict its use in this field. Attempts at improving the luminescence rise and decay time kinetics by introducing additional impurities have become a top priority task for many researchers. Analyzing literary data one can conclude that the optical parameters of co-doped crystals have been studied insufficiently or have not been studied at all. We have studied Ca2+ and Zr4+ co-doped Gd3Al2Ga3O12 : Ce single crystals by optical spectroscopy in the 200–2200 nm. We have taken the optical transmittance, absorption and reflection spectra and measured the refractive indices. Dispersion curves have been obtained by approximation of experimental refractive indices using the Brewster method and the Cauchy equation. Material constants of these equations have been estimated for each of the co-doped crystals.

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“…Using a small size pixel scintillators combined with Si-PM array is a possible method to improve the spatial resolution of the radiation imaging detectors. To develop scintillator with smaller pixels, a dicing method was developed [7]. By using the dicing method, GAGG [7,8] and LYSO plates [8] with 0.2 mm pixels were realized.…”

mentioning

confidence: 99%

“…To develop scintillator with smaller pixels, a dicing method was developed [7]. By using the dicing method, GAGG [7,8] and LYSO plates [8] with 0.2 mm pixels were realized. These 0.2 mm pixel size scintillator plates were optically coupled to Si-PM arrays to develop positon sensitive gamma detectors and evaluated the performance [7,8].…”

mentioning

confidence: 99%

Development of ultrahigh resolution radiation imaging detector using 1 mm channel size Si-PM array combined with 0.2 mm × 0.2 mm pixelated GAGG plate

et al. 2018

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A: For precise distribution measurements of gamma photons or beta particles, high resolution radiation imaging detectors are required. Reducing the size of the photodetectors combined with small pixel scintillators is a possible method to improve the spatial resolution of the scintillator based radiation imaging detectors. In this paper, we used a 1mm channel size silicon photomultiplier (Si-PM) array combined with a small pixel scintillator array and evaluated the performance for gamma photons and beta particles. For the radiation imaging detector, a Si-PM array with 1mm × 1mm channel size arranged in 8 × 8 (Hamamatsu, S13615-1025N-08) was optically coupled to a 0.2 mm × 0.2 mm pixelated GAGG plate. For 662 keV high energy gamma photons, 0.2mm GAGG pixels were clearly resolved in the position histogram. The peak to valley ratio (P/V) of the position histogram was not improved when only photo-peak events were used while it was improved when the events lower energy than the Compton edge was used. We could also resolve the position histograms for both 122 keV and 60 keV gamma photons. For beta particles, although the position histogram showed good separation for relatively low energy beta particles of Ca-45 (245 keV max), separation became worse for higher energy beta particles from Sr-Y-90 (545keV and 2280keV max). The separation of the position histogram for Sr-Y-90 improved when only lower energy events were used. Using 1mm size Si-PM array, high resolution detectors was realized for low energy gamma photons and beta particle but the spatial resolution was decreased for high energy beta particles from Sr-Y-90.

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Development of a high-precision color gamma-ray image sensor based on TSV-MPPC and diced scintillator arrays

Cited by 14 publications

References 11 publications

Beta‐ray imaging system with γ‐ray coincidence for multiple‐tracer imaging

Beta‐ray imaging system with γ‐ray coincidence for multiple‐tracer imaging

Effect of Ca 2+ and Zr 4+ co-doping on the optical properties of Gd 3Al 2Ga 3O 12: Ce single crystals

Development of ultrahigh resolution radiation imaging detector using 1 mm channel size Si-PM array combined with 0.2 mm × 0.2 mm pixelated GAGG plate

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