Development of a core-offset-based SMS fiber structure for detection of various biomolecules

Gu, Chaofan; Liu, Xuecheng; Lang, Xianzheng; Zhang, Wen; Singh, Ragini; Li, Guoru; Xie, Yiyan; Zhang, Bingyuan; Kumar, Santosh

doi:10.1364/ao.482927

Cited by 4 publications

(2 citation statements)

References 19 publications

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“…Fusion splicing is used to splice the MMF to both ends of the SMF, thereby creating the SMS structure. Careful and precise fusion splicing ensures low-loss connections between the fibers [12]. The splicing loss is kept below 0.01 dB while preparing the structure.…”

Section: Splicing Of Different Types Of Optical Fibersmentioning

confidence: 99%

Optical fiber-based LSPR biosensor for enhanced dopamine detection: advancing personalized healthcare

Sharma,

Choudhary,

Gupta

et al. 2024

Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV

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Dopamine, a vital neurotransmitter in the human body, plays a crucial role in various physiological functions and is closely associated with neurological disorders such as Parkinson's disease. Timely and accurate detection of dopamine levels is essential for effective disease management and personalized healthcare. In this study, we propose an innovative optical fiber-based biosensor utilizing the Localized Surface Plasmon Resonance (LSPR) effect for highly sensitive and selective dopamine detection. The biosensor probe is fabricated using a SMS (Single mode fiber-Multimode fiber-Single mode fiber) optical fiber structure, which is chemically modified to enhance the LSPR effect. Gold nanoparticles are employed to amplify the plasmonic response, enabling improved sensing performance. Experimental analysis is performed using dopamine samples, and the results are obtained using a spectrometer. The developed LSPR biosensor demonstrates great potential for precise and efficient dopamine detection, paving the way for advanced personalized healthcare and improved management of neurological disorders.

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Section: Splicing Of Different Types Of Optical Fibersmentioning

confidence: 99%

Optical fiber-based LSPR biosensor for enhanced dopamine detection: advancing personalized healthcare

Sharma,

Choudhary,

Gupta

et al. 2024

Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV

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“…Zhang [20] improved the Mach-Zehnder interference, accomplished torsion sensing, and decreased the cross sensitivity between torsion and temperature by employing the offset core construction. Gu et al [21] addressed the core shift sensor for biomolecule detection based on SMF and multimode fiber. The findings demonstrate the significant potential of the core offset structure in the creation of optical fiber sensors for biological detection.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Measurement of Microdisplacement and Temperature Based on Balloon-Shaped Structure

Zhang,

Liu,

Huang

et al. 2023

Sensors

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An optical fiber sensor for the simultaneous measurement of microdisplacement and temperature based on balloon-shaped single-mode fibers cascaded with a fiber Bragg grating with two core-offset joints is proposed. The interference between the core mode and cladding mode is caused by the stimulation of the cladding mode by the core-offset joints’ structure. The cladding of the core has a distinct refractive index, which causes optical path differences and interference. The balloon-shaped structure realizes mode selection by bending. As the displacement increases, the radius of the balloon-shaped interferometer changes, resulting in a change in the interference fringes of the interferometer, while the Bragg wavelength of the fiber grating remains unchanged. Temperature changes will cause the interference fringes of the interferometer and the Bragg wavelength of the fiber grating to shift. The proposed optical fiber sensor allows for the simultaneous measurement of microdisplacement and temperature. The results of the experiment indicate that the sensitivity of the interferometer to microdisplacement is 0.306 nm/µm in the sensing range of 0 to 200 μm and that the temperature sensitivity is 0.165 nm/°C, respectively. The proposed curvature sensor has the advantages of a compact structure, extensive spectrum of dynamic measurement, high sensitivity, and simple preparation, and has a wide range of potential applications in the fields of structural safety monitoring, aviation industry, and resource exploration.

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An Experimental Approach for the Detection and Analysis of Ascorbic Acid Using Optical Fiber-Based Biosensor with LSPR

Subbanna,

Choudhary,

Singh

et al. 2024

Plasmonics

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The presented artile is an exploratory proceed towards the diagnosis of Ascorbic Acid (AA) using the Localized Surface Plasmon Resonance (LSPR) methodology in conjunction with a Single-Mode-Step (SMS) optical ber structure. This fabricated biosensor presents simplicity, cost-effectiveness, and high sensitivity. To fabricate the suggested biosensor, aspeci ed length of optical ber is immersed witin a solution restrain AA. The outer surface of the ber is coated by gold nanoparticles, which generate localized surface plasmons when in contact by AA particles. The LSPR phenomenon results in a shift in the resonant wavelength of transmitted light, corresponding to AA absorptions. Laboratory appraisals have been conducted to optimize critical parameters, together with the length of the ber, nanoparticle size, concentration, including sensing mechanisms. These appraisals involved AA concentrations and gives a linear relationship inbetween wavelength shift as well as AA absorptions.This fabricated sensor shown a good stability and consistency. Additionally, this biosensor holds signi cant potential for applications in the elds of food inspection, clinical investigations, including pharmaceutical research. This laboratory work involves the development of LSPR biosensor based on optical ber structures, enhancing investigative capabilities.

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Development of a core-offset-based SMS fiber structure for detection of various biomolecules

Cited by 4 publications

References 19 publications

Optical fiber-based LSPR biosensor for enhanced dopamine detection: advancing personalized healthcare

Optical fiber-based LSPR biosensor for enhanced dopamine detection: advancing personalized healthcare

Simultaneous Measurement of Microdisplacement and Temperature Based on Balloon-Shaped Structure

An Experimental Approach for the Detection and Analysis of Ascorbic Acid Using Optical Fiber-Based Biosensor with LSPR

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