Development of a cone-shape phantom for multi-voxel MR spectroscopy

Woo, Dong‐Cheol; Kim, Bum Soo; Jung, Seungwon; Park, Hyo-Jin; Rhim, Hyangshuk; Jahng, Geon‐Ho; Choe, Bo-Young

doi:10.1016/j.jneumeth.2006.12.014

Cited by 9 publications

(10 citation statements)

References 33 publications

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“…This factor can be measured as the signal (initially) versus noise (after full relaxation) of the free induction decay (FID) spectrum in the time domain, or as the height of the largest metabolite peak divided by the noise in the frequency domain. The SNR of the metabolite peak depends on the metabolite concentrations (11,12,16,17); however, the concentration of water ($55.6 mM) in various MR phantoms is almost identical. (14) Therefore, the water resonance can be used as a reference for SNR calculations in different phantoms.…”

Section: Principal Quality Factors For Mrs Qa/qc Snrmentioning

confidence: 99%

“…We attempted to measure the localization and quantification accuracy by evaluating proportional relationships between the signal intensity of a metabolite and the quantity of the metabolite. A cone-shaped phantom was introduced in a previous study (16) as a possible tool for the evaluation of MR signals using the same concept. However, the use of this phantom in a previous study was confounded by air bubbles that caused susceptibility effects (55) in the cone-shaped vials due to a single opening to the inlet solution.…”

Section: Long-term Testmentioning

confidence: 99%

“…The correction factor was necessary, because the acrylic in the vial, in a selected voxel, causes a decrease in the water signal, although it does not affect distortions or artifacts on the MR spectrum (16,58). We determined the relative intensities of the water reference and the metabolites in order to perform a valid comparison among the MR spectra.…”

Section: Long-term Testmentioning

confidence: 99%

“…Although medical equipment manufacturers have provided MRS phantoms for QA/QC, these phantoms have offered limited information because the quantification and localization accuracy could not be evaluated due to the simple spherical shape. Recently, a multi-voxel spectroscopy (MVS) phantom has been developed with an array of cone-shaped vials for each brain metabolite (16). However, this multi-voxel spectroscopy phantom might be difficult to control due to its complex structure.…”

Section: Introductionmentioning

confidence: 99%

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Development of a QA phantom and protocol for proton magnetic resonance spectroscopy

Woo

Choi

Kim

et al. 2009

Concepts Magn Reson

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ABSTRACT:The purpose of this study was to develop a special proton magnetic resonance spectroscopy (1H-MRS) phantom, to establish and verify a quality assurance (QA) protocol, and to perform QA for a MR system. For a complete QA protocol, seven principal quality factors (PQFs) were measured. For evaluation of localization and quantification accuracy, two PQFs which are difficult to measure in commercial phantoms, we developed the layered dumbbell-shaped phantom. The performance sensitivity of our phantom was determined as a function of the voxel size on three occasions over $1 year. All MRS QA factors were optimized on two different MRI/MRS systems. The correlation between the metabolite signal intensity and the metabolite concentration was verified. The seven principal MRS QA factors studied can be used to evaluate MR spectra as well as to measure the stability of MR systems.

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Section: Principal Quality Factors For Mrs Qa/qc Snrmentioning

confidence: 99%

Section: Long-term Testmentioning

confidence: 99%

Section: Long-term Testmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Development of a QA phantom and protocol for proton magnetic resonance spectroscopy

Woo

Choi

Kim

et al. 2009

Concepts Magn Reson

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“…6,7 Detail phantoms utilizing acrylic or glass containers are vulnerable to susceptibility artifacts arising from the interface of the compartment wall material and the solution used to fill the phantom. 8 Those artifacts are more pronounced in high-detail and irregularly shaped phantoms.…”

Section: Introductionmentioning

confidence: 99%

A phantom to assess the accuracy of tumor delineation using MRSI

Heikal¹,

Wachowicz²,

Thomas³

et al. 2008

Radiology and Oncology

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Background. Studies have demonstrated that magnetic resonance spectroscopic imaging (MRSI) can detect regions of abnormal activity (tumor) that would not have been covered using conventional imaging and contouring methods. With increased interest in MRSI it is important that its accuracy in tumor delineation be investigated. While some effort has been made to design phantoms to examine the performance of MRSI sequences, most phantoms rely on using traditional glass or acrylic as the phantom building material. Material and methods. In this work, a gel-based detail phantom has been developed to assess the ability of the spectroscopic imaging sequences to accurately represent the geometry of tumors. The gel-based phantom is used as an alternative to conventional acrylic or glass based phantoms for use with MRSI. Results. Gel-based phantoms have the advantage of having a magnetic susceptibility close to that of water.In

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