Development of a comprehensive open access “molecules with androgenic activity resource (MAAR)” to facilitate risk assessment of chemicals
Fan Dong,
Barry Hardy,
Jie Liu
et al.
Abstract:The increasing prevalence of endocrine-disrupting chemicals (EDCs) and their potential adverse effects on human health underscore the necessity for robust tools to assess and manage associated risks. The androgen receptor (AR) is a critical component of the endocrine system, playing a pivotal role in mediating the biological effects of androgens, which are male sex hormones. Exposure to androgen-disrupting chemicals during critical periods of development, such as fetal development or puberty, may result in adv… Show more
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