Development of a coding SNP panel for tracking the origin of whole-exome sequencing samples
Yong Huang,
Yuanyuan Xiao,
Shengqiu Qu
et al.
Abstract:Whole-exome sequencing (WES) is widely used to diagnose complex genetic diseases and rare conditions. The implementation of a robust and effective quality control system for sample identification and tracking throughout the WES process is essential. We established a multiplex panel that included 22 coding single-nucleotide polymorphism (cSNP) loci. The personal identification and paternity identification abilities of the panel were evaluated, and a preliminary validation of the practical feasibility of the pan… Show more
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