Development of a Cell-Based Assay for Identification of Viral Entry Inhibitors Against SARS-CoV by High Throughput Screening (HTS)

Abstract

Purpose: Severe acute respiratory syndrome (SARS) is an atypical type of contagious pneumonia with a high mortality rate, however no effective drugs and vaccine were established. To identify an entry inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV), we have examined the effects of medicinal herbs which were found to be effective