“…This technique has been employed elsewhere to assess emissions from sewer systems (Hornberger and Spear, 1980;Chang and Delleur, 1992;Corsi and Birkett, 1995;Choi et al, 1998;Choi, 1998) for determining the relative importance of factors influencing the natural attenuation of mining contaminants (Choi et al, 1999) and in quantifying the importance of the parameters in models developed to describe the fate of volatile organic compounds in trickling filters (Parker, 1997). The MPSA approach allows an assessment of the importance of each input parameter at a variety of settings of the other input parameters (Rabinowitz and Steinberg, 1991;Parker, 1997;Choi et al, 1999) and thus provides a more realistic picture than the standard analyses (Deshusses, 1994;Stombaugh and Nokes, 1996;Liang et al, 2004;Xi et al, 2005;Baquerizo et al, 2005). Standard analyses assess each input parameter only at the default values of the other parameters (Rabinowitz and Steinberg, 1991;Hamby, 1994) while in MPSA; a pairwise evaluation of the parameters is performed to allow for the development of three-dimensional response curves.…”