Development of a biocompatible Ti-Nb alloy for orthopaedic applications

Fikeni, Lusanda; Annan, Kofi Ahomkah; Seerane, Mandy; Mutombo, Kalenda; Machaka, Ronald

doi:10.1088/1757-899x/655/1/012022

Cited by 7 publications

(3 citation statements)

References 8 publications

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“…Despite having a Young's modulus (around 110 GPa) higher than that of the cortical bone (around 10-30 GPa), this alloy is still employed for orthopedic implants [86] (see Figure 8). Nevertheless, the use of other titanium alloys such as Ti-7Nb [87], Ti-42Nb [3], β Ti-Nb-Sn [86], Ti-Nb-Zr [88], Ti-Nb-Ta-O [89], and Ti-Al-Nb [74]) (which could have a better performance) for the manufacture of such implants has recently been investigated. Niobium, zirconium, and tantalum (β-stabilizers) have shown to have adequate biocompatibility and nontoxicity [87].…”

Section: αþβ Alloysmentioning

confidence: 99%

Additive manufacturing of Ti6Al4V alloy via electron beam melting for the development of implants for the biomedical industry

Tamayo

Riascos

Vargas

et al. 2021

Heliyon

108

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Additive Manufacturing (AM) or rapid prototyping technologies are presented as one of the best options to produce customized prostheses and implants with high-level requirements in terms of complex geometries, mechanical properties, and short production times. The AM method that has been more investigated to obtain metallic implants for medical and biomedical use is Electron Beam Melting (EBM), which is based on the powder bed fusion technique. One of the most common metals employed to manufacture medical implants is titanium. Although discovered in 1790, titanium and its alloys only started to be used as engineering materials for biomedical prostheses after the 1950s. In the biomedical field, these materials have been mainly employed to facilitate bone adhesion and fixation, as well as for joint replacement surgeries, thanks to their good chemical, mechanical, and biocompatibility properties. Therefore, this study aims to collect relevant and up-to-date information from an exhaustive literature review on EBM and its applications in the medical and biomedical fields. This AM method has become increasingly popular in the manufacturing sector due to its great versatility and geometry control.

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Section: αþβ Alloysmentioning

confidence: 99%

Additive manufacturing of Ti6Al4V alloy via electron beam melting for the development of implants for the biomedical industry

Tamayo

Riascos

Vargas

et al. 2021

Heliyon

108

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“…This is because of their excellent biocompatibility, and desired mechanical properties such as low elastic modulus and improved resistance to corrosion [11][12][13]. Currently there are several variants of titanium alloys that are available such as Cp-Ti [14], Ti6Al4V [15], Ti-Nb-Sn [16], Ti-Nb-Zr [17], Ti-Nb [18], Ti-Fe [19], Ti Mo [20], Ti-Cu [21], and Ti-Fe-Nb [22]. However, Cp-Ti and Ti6Al4V are predominantly utilized clinically owing to their enhanced mechanical properties such as high strength, low modulus of elasticity, improved biocompatibility, and excellent resistance to corrosion [23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Ti-Sn Alloy for Orthopedic Application

2021

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Titanium (Ti)-based alloys (e.g., Ti6Al4V) are widely used in orthopedic implant applications owing to their excellent mechanical properties and biocompatibility. However, their corrosion resistance needs to be optimized. In addition, the presence of aluminum and vanadium cause alzheimer and cancer, respectively. Therefore, in this study, titanium-based alloys were developed via powder metallurgy route. In these alloys, the Al and V were replaced with tin (Sn) which was the main aim of this study. Four sets of samples were prepared by varying Sn contents, i.e., 5 to 20 wt. %. This was followed by characterization techniques including laser particle analyzer (LPA), X-ray diffractometer (XRD), scanning electron microscope (SEM), computerized potentiostate, vicker hardness tester, and nanoindenter. Results demonstrate the powder sizes between 50 and 55 µm exhibiting very good densification after sintering. The alloy contained alpha at all concentrations of Sn. However, as Sn content in the alloy exceeded from 10 wt. %, the formation of intermetallic compounds was significant. Thus, the presence of such intermetallic phases are attributed to enhanced elastic modulus. In particular, when Sn content was between 15 and 20 wt. % a drastic increase in elastic modulus was observed thereby surpassing the standard/reference alloy (Ti6Al4V). However, at 10 wt. % of Sn, the elastic modulus is more or less comparable to reference counterpart. Similarly, hardness was also increased in an ascending order upon Sn addition, i.e., 250 to 310 HV. Specifically, at 10 wt. % Sn, the hardness was observed to be 250 HV which is quite near to reference alloy, i.e., 210 HV. Moreover, tensile strength (TS) of the alloys were calculated using hardness values since it was very difficult to prepare the test coupons using powders. The TS values were in the range of 975 to 1524 MPa at all concentrations of Sn. In particular, the TS at 10 wt. % Sn is 1149 MPa which is comparable to reference counterpart (1168 MPa). The corrosion rate of Titanium-Sn alloys (as of this study) and reference alloy, i.e., Ti6Al4V were also compared. Incorporation of Sn reduced the corrosion rate at large than that of reference counterpart. In particular, the trend was in decreasing order as Sn content increased from 5 to 20 wt. %. The minimum corrosion rate of 3.65 × 10−9 mm/year was noticed at 20 wt. % than that of 0.03 mm/year of reference alloy. This shows the excellent corrosion resistance upon addition of Sn at all concentrations.

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“…It has however been pointed out that the above stated difficulties associated with the production process can be overcome through the use of powder metallurgy and the solid state production techniques [15,16]. Mechanical alloying (MA) which is a powder metallurgy process has been identified as a feasible and promising route for cost effective production of Ti based alloys [16][17][18]. One major problem identified with the MA is the contamination with the milling media and container, which are associated with the processing parameters such as speed, time and ball to powder weight ratio [15].…”

Section: Introductionmentioning

confidence: 99%