Abstract:This paper proposes a high-performance liquid chromatography (HPLC) method for the simultaneous estimation of nortriptyline and gabapentin. The analytical conditions of the method were selected based on the chemical nature of the two compounds, and the method was validated through various studies including system suitability, specificity, linearity, LOD/LOQ, and recovery studies. The proposed method uses a Zorbax C18 column, a phosphate buffer with an acidic pH, and acetonitrile as the organic constituent of t… Show more
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