Development and validation of an analytical procedure to detect spatio-temporal differences in antidepressant use through a wastewater-based approach

High-throughput wastewater analysis for substance use assessment in central New York during the COVID-19 pandemic

“…where mass load represents the daily mass load of a substance entering a WWTP (g d À1 ), C W is the aqueous concentration of a substance in wastewater (ng L À1 ), Q is the average daily ow rate of wastewater measured at the inlet of a WWTP (m 3 d À1 ), stability is the in-sewer stability change of a substance (%; assuming <10% according to previous WBE studies [66][67][68] given the relatively short sewer transit times in the studied sewersheds), consumption rate is the collective consumption of a substance (i.e., consumed and disposed) by a given population (mg per d per 1000 people), excretion is the average excretion rate of a parent compound or its metabolite reported in the pharmacokinetic literature and WBE studies, 65,[68][69][70][71][72][73][74][75][76][77][78][79] MW Parent is the molecular weight of a parent compound, MW Metabolite is the molecular weight of a stable metabolite when present, and population is the number of residents served by a given WWTP (assuming no substantial variations due to travel restrictions 80 ).…”

Current and future perspectives for wastewater-based epidemiology as a monitoring tool for pharmaceutical use

“…45 out of the 64 studies demonstrate the ability of WBE to investigate spatial differences in the consumption of pharmaceuticals (Ahmed et al, 2020;Australian Crime Intelligence Commision, 2020;Bade, Ghetia, White, & Gerber, 2020;Baker, Ocenaskova, Kvicalova, & Kasprzyk-Hordern, 2012;Baz-Lomba et al, 2016;Bodik et al, 2016;Boogaerts, Degreef, Covaci, & van Nuijs, 2019;Boogaerts, Quireyns, Covaci, De Loof, & van Nuijs, 2021;Burgard, Fuller, Becker, Ferrell, & Dinglasan-Panlilio, 2013;Castrignano et al, 2020;Causanilles, Emke, & de Voogt, 2016;Causanilles et al, 2018Causanilles et al, , 2017P. M. Choi et al, 2018;Croft, Huffines, Pathak, & Subedi, 2020;Duan, Meng, Wen, & Chen, 2013;Escolà Casas et al, 2021;Fáberová, Bodík, Ivanová, Grabic, & Mackuľak, 2017;Fallati et al, 2020;Gao et al, 2016;Gomez-Canela, Sala-Comorera, Pueyo, Barata, & Lacorte, 2019;Gushgari, Driver, Steele, & Halden, 2018;Kim & Oh, 2020;Krizman, Senta, Ahel, & Terzic, 2016;Mackulak et al, 2016Mackulak et al, , 2019Mirzaei, Mesdaghinia, Hoseini, & Yunesian, 2019;Ort, Lawrence, Reungoat, Eaglesham, et al, 2010;Ostman, Fick, Nasstrom, & Lindberg, 2014;Pereira et al, 2015;Riva, Castiglioni, Pacciani, & Zuccato, 2020;Shao et al, 2021;Skees, Foppe, Loganathan, & Subedi, 2018;Subedi, Balakrishna, Joshua, & Kan...…”

Micropollutant fluxes in urban environment – A catchment perspective

“…There are many studies that detail the presence of a range of compounds in a variety of matrices, however the majority of this existing work has been focused on one or two classes at a time, or a small number of compounds of emerging concern (CECs), primarily in aqueous matrices (Boogaerts et al, 2019;Loos et al, 2009;Mole and Brooks, 2019;Musolff et al, 2009;Petrie et al, 2014a). There is a broad range of existing data from a variety of studies (Geissen et al, 2015;Petrie et al, 2014a;Sousa et al, 2018) but due to the large number of potential substances, matrices, methods, and multiple lines of investigation that can be pursued, comparisons between the studies are limited due to the different methods utilised, as they have different quantification parameters.…”