Development and validation of an ICD-10-based disability predictive index for patients admitted to hospitals with trauma

Wada, Tomoki; Yasunaga, Hideo; Yamana, Hayato; Matsui, Hiroki; Fushimi, Kiyohide; Morimura, Naoto

doi:10.1016/j.injury.2017.12.021

Cited by 6 publications

(1 citation statement)

References 25 publications

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“…We extracted and analyzed the data from the Japanese nationwide Diagnosis Procedure Combination (DPC) database, the details of which have been described previously, elsewhere [23][24][25]. In short, the DPC database includes summary and administrative claims data for all patients discharged from more than 1000 hospitals in Japan.…”

Section: Data Source and Variablesmentioning

confidence: 99%

Haptoglobin use and acute kidney injury requiring renal replacement therapy among patients with severe burn injury: a nationwide database study

et al. 2019

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a BStra ct BackgrOundPrevious studies have suggested that haptoglobin may be beneficial for preventing acute kidney injury (AKI) after severe burns. Although haptoglobin has been approved for the treatment of haemoglobinuria and subsequent AKI in Japan, robust evidence for this is lacking. We examined whether haptoglobin may be effective in preventing AKI requiring renal replacement therapy among patients with severe burns. MethOdSWe performed propensity score-matched analyses of the Japanese nationwide Diagnosis Procedure Combination inpatient database. We identified patients with severe burns (burn index ≥ 10) whose data were recorded from 1 July 2010 to 31 March 2013. We compared patients who were administered haptoglobin within 2 days of admission (haptoglobin group) and those who were not administered haptoglobin (control group). The main outcomes were: requirement for renal replacement therapy during admission, 28-day inhospital mortality, length of hospital stay and ventilator-free days. reSultS Eligible patients (n = 3223) from 618 hospitals were categorized into either the haptoglobin group (n = 263) or the control group (n = 2960). Propensity score matching created a matched cohort of 185 pairs with and without haptoglobin. There were no significant differences between the propensity score-matched groups in terms of the proportion of patients requiring renal replacement therapy (control vs haptoglobin, 25.9% vs 31.9%; p = 0.25), ventilator-free days (13 vs 6 days, p = 0.95), length of hospital stay (38 vs. 27, p = 0.45) and 28-day mortality (42.7% vs 46.5%, p = 0.53). cOncluSiOnS Our results suggest that haptoglobin use is not associated with reduced requirement for renal replacement therapy, increased ventilator-free days, length of hospital stay, or reduced 28-day mortality in patients with severe burns.

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Section: Data Source and Variablesmentioning

confidence: 99%