Development and validation of an ion-pair HPLC method for determination of perchlozone in blood plasma

Ramenskaya, G. V.; Smerdin, Sergey; Medvedev, Yu. V.; Шохин, И. Е.; Yarushok, T. A.; Savchenko, A. Yu.; Karlina, V. Yu.

doi:10.1007/s11172-014-0585-8

Search citation statements

Order By: Relevance

Paper Sections

Select...

Results1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 5 publications

(1 reference statement)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to [21] specificity is the ability of the procedure to detect analyte in the presence of components that can be contained in the sample. The procedure specificity was determined using the technique described in [22]. Six samples of pure (containing no analyte) urine and samples of urine with added meldonium solution at precisely known concentration were studied in parallel.…”

Section: Resultsmentioning

confidence: 99%

Electrochemical Sensor for Selective Detection of Meldonium in Urine by Voltammetry

et al. 2022

View full text Add to dashboard Cite

A highly sensitive electrochemical sensor based on arenediazonium tosylates was designed to detect meldonium in urine. The effect of the concentration of ArN2 + OTs À arenediazonium tosylate modifier and various substituents was studied. Basic operating parameters for voltammetric meldonium detection were established and the procedure for urine sample preparation was developed. The following values were obtained: limit of detection (LOD) 0.005 mg • L À 1 (P = 0.95) and limit of quantification (LOQ) 0.01 mg • L À 1 . The relationship between the analytical signal and meldonium concentration in the solution ranging from 0.01 to 400 mg • L À 1 was described by a linear function. The meldonium concentration error did not exceed 18 %. The analysis time for a single urine sample was reduced to 15 minutes.

show abstract

Section: Resultsmentioning

confidence: 99%