Abstract:Caffeine and guarana are safe foods according to the American (FDA) and Brazilian (ANVISA) health agencies. However, data regarding the composition, quality, and safety of guarana-based food supplements sold in Brazil are limited. Most of the methods used for quantification of caffeine and other guarana chemical markers are based on complex extraction techniques as well as on gradient elution and do not evaluate the matrix effect nor the uncertainty estimation measurement. A simple and selective method for caf… Show more
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