Development and validation of a case definition for epilepsy for use with administrative health data

Reid, Aylin Y.; Germaine-Smith, Christine St.; Liu, Mingfu; Sadiq, Shahnaz; Quan, Hude; Wiebe, Samuel; Faris, Peter; Dean, Stafford; Jetté, Nathalie

doi:10.1016/j.eplepsyres.2012.05.009

Cited by 107 publications

(156 citation statements)

References 13 publications

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“…Seizures were identified through emergency room and hospitalization records using validated ICD-9 and ICD-10 codes. 21,22 We then excluded records with invalid or inaccurate information and all patients younger than 18 years at the time of the seizure. We further excluded patients with a diagnosis of a brain tumor in the previous 5 years as occasionally patients with brain tumors undergo surgery because of focal neurologic deficits, the tumor's nature (e.g., malignancy), and not because their seizures are refractory to medical treatment.…”

Section: Methods Study Designmentioning

confidence: 99%

Disparities in surgery among patients with intractable epilepsy in a universal health system

et al. 2016

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Objective: To assess the use of epilepsy surgery in patients with medically intractable epilepsy in a publicly funded universal health care system. Methods:We performed a population-based retrospective cohort study using linked health care databases for Ontario, Canada, between 2001 and 2010. We identified all patients with medically intractable epilepsy, defined as those with seizures that did not respond to at least 2 adequate trials of seizure medications. We assessed the proportion of patients who had epilepsy surgery within the following 2 years. We further identified the characteristics associated with epilepsy surgery.Results: A total of 10,661 patients were identified with medically intractable epilepsy (mean age 47 years, 51% male); most (74%) did not have other comorbidities. Within 2 years of being defined as medically intractable, only 124 patients (1.2%) underwent epilepsy surgery. Death occurred in 12% of those with medically intractable epilepsy. Those who underwent the procedure were younger and had fewer comorbidities compared to those who did not. Conclusion:In our setting of publicly funded universal health care, more than 10% of patients died within 2 years of developing medically intractable epilepsy. Epilepsy surgery may be an effective treatment for some patients; however, fewer than 2% of patients who may have benefited from epilepsy surgery received it.

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Section: Methods Study Designmentioning

confidence: 99%

Disparities in surgery among patients with intractable epilepsy in a universal health system

et al. 2016

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“…Previous epidemiologic studies [11][12][13][14] have found that these data sources have a high level of completeness and validity. Physicians must submit diagnostic codes (up to 3 per visit) to be reimbursed under the feefor-service insurance plan, and relatively few Alberta physicians (< 7%) are on alternate payment plans, compared with other Canadian provinces.…”

Section: Study Setting and Data Sourcesmentioning

confidence: 99%

Risk of febrile seizures after first dose of measles–mumps–rubella–varicella vaccine: a population-based cohort study

MacDonald

Dover

Simmonds

et al. 2014

CMAJ

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“…Although individuals responsible for ICD coding in the DAD receive standardized training in Canada (33), there may still be coding variations across provinces that could limit the generalizability of these findings. Previous studies have compared the validity of case identification using administrative data against chart review in the areas of hypertension and diabetes mellitus, and found that the sensitivity results (diabetes mellitus range 90.2-92.1%, hypertension range 74.0-76.0%) are not significantly different between 2 provinces (Alberta and British Columbia) (21,24).…”

Section: Discussionmentioning

confidence: 99%

Estimating the Burden of Osteoarthritis to Plan for the Future

Marshall

Vanderby

Barnabé

et al. 2015

Arthritis Care & Research

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Objective. With aging and obesity trends, the incidence and prevalence of osteoarthritis (OA) is expected to rise in Canada, increasing the demand for health resources. Resource planning to meet this increasing need requires estimates of the anticipated number of OA patients. Using administrative data from Alberta, we estimated OA incidence and prevalence rates and examined their sensitivity to alternative case definitions. Methods. We identified cases in a linked data set spanning 1993 to 2010 (population registry, Discharge Abstract Database, physician claims, Ambulatory Care Classification System, and prescription drug data) using diagnostic codes and drug identification numbers. In the base case, incident cases were captured for patients with an OA diagnostic code for at least 2 physician visits within 2 years or any hospital admission. Seven alternative case definitions were applied and compared. Results. Age-and sex-standardized incidence and prevalence rates were estimated to be 8.6 and 80.3 cases per 1,000 population, respectively, in the base case. Physician claims data alone captured 88% of OA cases. Prevalence rate estimates required 15 years of longitudinal data to plateau. Compared to the base case, estimates are sensitive to alternative case definitions. Conclusion. Administrative databases are a key source for estimating the burden and epidemiologic trends of chronic diseases such as OA in Canada. Despite their limitations, these data provide valuable information for estimating disease burden and planning health services. Estimates of OA are mostly defined through physician claims data and require a long period of longitudinal data.

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Development and validation of a case definition for epilepsy for use with administrative health data

Cited by 107 publications

References 13 publications

Disparities in surgery among patients with intractable epilepsy in a universal health system

Disparities in surgery among patients with intractable epilepsy in a universal health system

Risk of febrile seizures after first dose of measles–mumps–rubella–varicella vaccine: a population-based cohort study

Estimating the Burden of Osteoarthritis to Plan for the Future

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