Development and Validation of a LASSO Prediction Model for cisplatin induced nephrotoxicity: A Case-Control Study in China
Jingwei Zhang,
Xuyang Luo,
Yi Fan
et al.
Abstract:Background: Early identification of high-risk individuals with cisplatin-induced nephrotoxicity (CIN) is crucial for avoiding CIN and improving prognosis. In this study, we developed and validated a CIN prediction model based on general clinical data, laboratory indications, and genetic features of lung cancer patients before chemotherapy.
Method: We retrospectively included 696 lung cancer patients using platinum chemotherapy regimens from June 2019 to June 2021 as the test set to construct a predictive mod… Show more
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