Development and validation of a UPLC-PDA method for quantifying ceftazidime in dried blood spots

Lv, Jianmei; Wu, Qiping; Li, Sanwang; Yi, Hanxi; Xie, Feifan

doi:10.1016/j.jpba.2023.115928

Cited by 1 publication

(1 citation statement)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For the evaluation of natural products, the use of DAD and PDA detectors is necessary since they enable the detection and identification of compounds based on their UV-Vis absorption spectra, which is a process with higher sensitivity compared to other detectors such as UV-Vis or refractive index detectors [ 72 , 73 ]. Even though DAD and PDA detectors are exploited in the investigation of bioactive compounds, it is crucial to mention that PDA detectors are preferred since they exhibit higher sensitivity, better signal-to-noise ratio, high data acquisition rates, higher spectral resolution, and advanced data processing [ 74 ].…”

Section: Carotenoids: Sources Extraction Characterization and Activit...mentioning

confidence: 99%

Recent Advances in the Therapeutic Potential of Carotenoids in Preventing and Managing Metabolic Disorders

Ortega-Regules,

Martínez-Thomas,

Schürenkämper-Carrillo

et al. 2024

Plants

View full text Add to dashboard Cite

Carotenoids constitute compounds of significant biological interest due to their multiple biological activities, such as antimicrobial, anticancer, antiadipogenic, antidiabetic, and antioxidant properties. Metabolic syndrome (MetS) comprehends a series of metabolic abnormalities (e.g., hypertension, obesity, and atherogenic dyslipidemia) that can affect children, adolescents, and the elderly. The treatment of MetS involves numerous medications, which, despite their efficacy, pose challenges due to prolonged use, high costs, and various side effects. Carotenoids and their derivatives have been proposed as alternative treatments to MetS because they reduce serum triglyceride concentrations, promote insulin response, inhibit adipogenesis, and downregulate angiotensin-converting enzyme activity. However, carotenoids are notably sensitive to pH, light exposure, and temperature. This review addresses the activity of carotenoids such as lycopene, lutein, fucoxanthin, astaxanthin, crocin, and β-carotene towards MetS. It includes a discussion of sources, extraction methods, and characterization techniques for analyzing carotenoids. Encapsulation approaches are critically reviewed as alternatives to prevent degradation and improve the biological performance of carotenoids. A brief overview of the physiopathology and epidemiology of the diseases, including MetS, is also provided.

show abstract

Section: Carotenoids: Sources Extraction Characterization and Activit...mentioning

confidence: 99%

Recent Advances in the Therapeutic Potential of Carotenoids in Preventing and Managing Metabolic Disorders

Ortega-Regules,

Martínez-Thomas,

Schürenkämper-Carrillo

et al. 2024

Plants

View full text Add to dashboard Cite

show abstract

Development and validation of a UPLC-PDA method for quantifying ceftazidime in dried blood spots

Cited by 1 publication

References 22 publications

Recent Advances in the Therapeutic Potential of Carotenoids in Preventing and Managing Metabolic Disorders

Recent Advances in the Therapeutic Potential of Carotenoids in Preventing and Managing Metabolic Disorders

Contact Info

Product

Resources

About