Development and validation of a pyroptosis-related prognostic signature associated with osteosarcoma metastasis and immune infiltration
Zhenyu Gong,
Yimo Wan,
Enen Han
et al.
Abstract:Pyroptosis is a programmed cell death, which has garnered increasing attention because it relates to the immune and therapy response. However, few studies focus on the application of pyroptosis-related genes (PRGs) in predicting osteosarcoma (OS) patients’ prognoses. In this study, the gene expression and clinical information of OS patients were downloaded from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database. Based on these PRGs and unsupervised clustering analysis, a… Show more
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