Development and Validation of a Simoa Assay for Determination of Recombinant Batroxobin in Human Serum

Preparation of arsenic(iii) monoclonal antibodies and preliminary evaluation of a novel silver-coated gold nanorod SERS immunoassay strip construction

“…The four carboxyl groups of ITCBE can chelate As 3+ , and its benzyl isothiocyanate group can also couple with the surface amino groups of the carrier protein. 30,38,39 This crosslinking and aggregation of protein moieties reduce their solubility and enhance the immunogenicity of the antigen, thereby facilitating the preparation and Paper Analytical Methods identication of arsenic immunogens. In this study, ITCBE was utilized to chelate As 3+ while simultaneously conjugating to macromolecular proteins.…”