Background: In order to measurement of career problems of bipolar mood patients, this study was performed on the 108 people that were selected by purposeful sampling, which were consisted of two sample groups (non-clinical participants, N= 53) and (bipolar participants, N= 55). Method: The inventory is including 81 items. In order to determine the reliability of CPI-BD was used internal consistency and temporal stability method. Factor analysis was investigated and content, construct and convergent validity of the CPI-BD was evaluated.Results: Coefficient Cronbach's alpha was .81 (non-clinical participants, N= 53) and .96 (bipolar participants, N= 55), (p<0.05) and showed good internal consistency. Also in temporal stability method test-retest reliability about 7 weeks later, includes 35 participants from both the non-clinical participants and bipolar patients obtaining a reliability coefficient of .91 (p<0.01). Convergent validity of this inventory was examined with Bipolar disorder symptom inventory (BDSI) and correlation coefficient was obtained r=.79 (non-clinical participants, N= 53) and r=.78 (bipolar participants, N= 55) (p<0.01). In exploring factor analysis using varimax rotation nine sub-scales were extracted, including: communication problems, poor work performance, insecurity, grandiosity, unreliability, change seeking, vulnerability, lack of boundary, lack of self-control with the opposite sex.Conclusion: The career problems inventory–bipolar disorder form is a valid and reliable inventory to measure career problems among bipolar patients.