Development and proof-of-concept demonstration of a clinical metagenomics method for the rapid detection of bloodstream infection
Lluis Moragues-Solanas,
Thanh Le-Viet,
Elinor McSorley
et al.
Abstract:Background
The timely and accurate diagnosis of bloodstream infection (BSI) is critical for patient management. With longstanding challenges for routine blood culture, metagenomics is a promising approach to rapidly provide sequence-based detection and characterisation of bloodborne bacteria. Long-read sequencing technologies have successfully supported the use of clinical metagenomics for syndromes such as respiratory illness, and modified approaches may address two requisite factors for metag… Show more
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